方法：按Cochrane系统评价方法，计算机检索Medline(1966-01/2011-03)、EMbase(1966/2010年)、Cochrane图书馆(2010年)、万方数据库、维普数据库、中国知网数据库，纳入中医药治疗青光眼的随机及半随机对照试验，并按Cochrane协作网提供的RevMan 5.0统计软件进行质量评价、资料提取和Meta分析。

结果：共纳入8个随机对照研究文献，包括719例患者。Meta分析结果显示：中医药联合西医治疗青光眼在保护视神经、维持最佳矫正视力方面较单纯使用西医的效果更佳(P<0.01)。但因纳入研究数量少，且方法学上存在不同程度的缺陷，故其证据强度较低，需要更多严格设计的大样本和多中心的研究以提高针刺疗效的证据强度。

结论：研究显示，相对于单纯西医治疗青光眼，中西医结合在治疗青光眼方面能保护视功能、维持视力及总体疗效上起到明显的效果。但限于目前研究中医药保护青光眼患者视功能的文献报道质量低、数目有限，仍然需要大样本、多中心随机对照试验，以进一步证实中医药治疗青光眼的优越性。

METHODS:The electronic bibliographic databases were searched,including Medline(1966-01/2011-03), EMbase(1996-2010), Cochrane library, Wanfang database,VIP(1999-2011), CNKI, the radomized controlled trials of TCM treatment compares with Western medicine treatment of the glaucoma were assembled Data were extracted and evaluated by two reciewers independently with a designed extraction formation by Meta-analysis based on the Cochrane net suggestion.

RESULTS:A total of 8 theses written in Chinese were retrieved,including 719 patients.The results of Meta-analysis showed the combination therapy of TCM and western therapy significant improves the effect of neuroprotection(P<0.01). In order to boost and qualify the curative effects of the aucupuncture, more precise samples should be designed and a multi-research central need to be bulit. however, according to the existing cases, the evidences of the effectiveness are weak due to the limited numbers of samples and the methodological defect.

CONCLUSION: The existing evidence supports the combination therapy of TCM and western medicine stronger than the only used of western medicine(P<0.01). But owing to the limited studies and few number of TCM treatment for glaucoma's neuroprotection, the large sample andmulticenter random ized controlled trial is still needed to verify the superiority of TCM for neuroproctive effect of glaucoma's teatment.