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[摘要]
目的：观察氩激光视网膜光凝治疗中心性浆液性脉络膜视网膜病变(简称中心性浆液性脉络膜视网膜病变)的疗效。
方法：治疗组18例18眼，予氩激光视网膜光凝，同时口服卵磷脂络合碘、维生素B1、肌苷、维脑路通片等药物。对照组18例18眼口服卵磷脂络合碘、维生素B1、肌苷、维脑路通片等药物。分别于治疗前、1mo后、3mo后OCT测量黄斑中心凹厚度及神经上皮层脱离范围，比较两组黄斑中心凹厚度及神经上皮层脱离范围下降值。
结果：治疗后1mo，OCT检查中心凹厚度下降值：治疗组256±72μm，对照组82±57μm，两组比较差异有统计学意义(P<0.05)； 神经上皮层脱离范围下降值：治疗组3 548μm±168μm，对照组1 520±143μm，两组比较差异有统计学意义(P<0.05)。治疗3mo后复查，OCT检查中心凹厚度下降值：治疗组383±75μm，对照组312±67μm，两组比较差异有统计学意义(P<0.05)； 神经上皮层脱离范围下降值：治疗组4 908±172μm，对照组4 211±153μm，两组比较差异有统计学意义(P<0.05)。
结论：氩激光视网膜光凝治疗中心性浆液性脉络膜视网膜病变是一有效治疗方法，能明显缩短病程。
[Key word]
[Abstract]
AIM: To observe the efficacy of the argon laser photocoagulation treatment of central serous chorioretinopathy(CSC).
METHODS: The treatment groups: 18 patients(18 eyes), argon laser photocoagulation and oral jolethin, vitamin B1, inosine and venoruton tablets. Control group: 18 patients(18 eyes), oral lecithin complex iodine, vitamin B1, inosine, venoruton tablets. Foveal thickness and neuroepithelial layer detachment range were measured by optical coherence tomography(OCT)before treatment, after 1 month and 3 months post-operation to compare the decline in value of foveal thickness and neuroepithelial layer detachment range of the two groups.
RESULTS: After 1 month of treatment, the decline in value of the center foveal thickness: the value of treatment group was 256±72μm; the value of the control group was 82±57μm, and the difference of the two groups, P <0.05; the decline in value of neuroepithelial layer detachment range: the value of the treatment group was 3 548±168μm, the value of the control group was 1 520±143μm, And the difference of the two groups, P<0.05. After three months of treatment, the decline in value of the center foveal thickness: the value of treatment group was 383±75μm, the value of the control group was 312±67 μm, and the difference of the two groups, P<0.05; decline in value of neuroepithelial layer detachment range: the value of the treatment group was 4 908±172μm, the value of the control group was 4 211±153μm, and the difference of the two groups, P <0.05. The differences were statistically significant between the treatment and the control groups(two independent samples t-test).
CONCLUSION:Argon laser photocoagulation treatment of CSC is an effective treatment method and can significantly shorten the course.
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