方法：收集2011-07/2012-12经药物治疗无效的感染性角膜溃疡患者8例，采用游离结膜瓣移植手术治疗，术中清除角膜表面溶解坏死组织，上穹隆环钻刻切全厚游离结膜瓣，覆盖角膜病变区域，10-0尼龙线间断缝合8～12针，线结埋于角膜基质，配戴角膜接触镜，术后继续药物治疗原发病。

结果：全部患者术后感染控制无复发，游离结膜瓣贴敷良好，缝线拆除后结膜瓣无松脱，眼表规则，泪膜涂布良好，术后视力均不同程度提高。

结论：游离结膜瓣移植术治疗难治性角膜溃疡安全有效。

METHODS: From July 2011 to November 2012, eight patients(8 eyes)with serious corneal ulcer who underwent conjunctival flap transplantation were retrospectively analyzed. The ulcers were covered with full-thickness free conjunctival flaps and were interrupted sutures. The patients wore contact lens and took medical treatment after operation.

RESULTS: Postoperatively, the corneal ulcer in 8 eyes was cured after one surgery and whose conjunctiva flaps were good. The conjunctiva flaps were not desquamated after took out stitches. The ocular surface was regular. The visual acuity was improved in different degrees.

CONCLUSION: Free conjunctival flap transplantation is safe and effective in the treatment of refractory corneal ulcers.