方法：分析一次治疗失败的32眼新生儿泪囊炎患儿，采用二次鼻泪管探通后的治疗效果，并对一次探通成功的115眼患儿的探针进针深度进行统计。

结果：由于泪道探通的有效率与年龄有关，本研究三组患儿的年龄构成差异无统计学意义(P>0.05)。按间隔时间分组，1wk以内的11只患眼中，经二次治疗有效10眼，占91%； 1～2wk的13只患眼中， 有效12眼，占92%； 2wk以上8只患眼中， 有效6眼，占75%。有效率差异有统计学意义，间隔1～2wk二次治疗的成功率最高，并发症发生率最低(P<0.05)。<3月龄患儿操作中进针深度24～26.5mm，3～7月龄26.5～28.5mm，7～12月龄28.5～30mm，12～36月龄30～32.5mm。

结论：间隔1～2wk再行二次治疗的成功率最高，并发症发生率最低，是最佳治疗时机。操作中，<3月龄患儿操作中进针深度24～26.5mm，3～7月龄26.5～28.5mm，7～12月龄28.5～30mm，12～36月龄30～32.5mm。

METHODS: The treatment effect of the second lacrimal passage after the first treatment failure was analyzed and the depth of the needle was studied.

RESULTS: Due to the recovery rate of the lacrimal passage is related to age, there was no statistically significant difference in age, among the three groups(P>0.05). Divided according to timing, 10 eyes were cured by secondary treatment in less than 1 week, accounting for 91%; 12 eyes were cured in 1-2 weeks, accounting for 92%; 6 eyes were cured in more than 2 weeks, accounting for 75%. There was statistically significant difference in achievement ratio(P>0.05). The achievement ratio was the highest and the complication ratio was the lowest in 1-2 weeks.

CONCLUSION: 1-2 weeks is the best timing of secondary treatment.