[关键词]
[摘要]
血氧饱和度水平依赖性功能性核磁共振(BOLD- fMRI)利用血液中脱氧血红蛋白这一内源性顺磁物质作为对比剂，获得大脑皮层血管内MRI信号变化，从而得到大脑激活区域的图像，由于其定位精确、直观，属无创性检查，应用领域广泛，为弱视神经发生机制、眼优势柱、视觉运动觉及色觉等方面的研究提供了可视和客观的依据。
[Key word]
[Abstract]
Blood oxygen level dependence-functional magnetic resonance imaging(BOLD-fMRI)utilizing the endogenous paramagnetic material-deoxygenated hemoglobin as a contrast agent gains signal changes of MRI in cortical intravascular and obtains images of the active area. Due to accurate location, intuitive and noninvasive, BOLD-fMRI is applied widely and provides objective evidence for amblyopia neurogenesis mechanism, ocular dominance column, motion perception and color vision.
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