方法：选择我院80例86眼难治性青光眼患者，随机分为复合式小梁切除术联合羊膜植入术组(实验组)43眼和复合式小梁切除术组(对照组)43眼。观察术后眼压、滤过泡形成情况及并发症。

结果：随诊12mo，平均眼压：实验组15.5±1.1mmHg，对照组19.7±2.5mmHg，两组术后平均眼压差异有统计学意义(P<0.05)； 功能性滤过泡：实验组(86%)较对照组(67%)多，差异有统计学意义(P<0.05)； 术后并发症(浅前房、脉络膜脱离和滤过泡渗漏)发生率实验组明显低于对照组。

结论：复合式小梁切除联合羊膜植入术治疗青光眼具有手术成功率高，术后并发症发生率低的特点。

METHODS: Totally 86 eyes of 80 glaucoma patients were randomly divided into 2 groups. In experimental group, 43 eyes underwent trabeculectomy combined with bio-amnion implantation. In control group, 43 eyes only underwent trabeculectomy combined. The intraocular pressure(IOP), filtrative bleb and complications were observed.

RESULTS: Following-up for 12 months, IOP: there was significant difference between the average IOP(15.5±1.1mmHg)in experimental group and the average IOP(19.7±2.5mmHg)in control group(P<0.05). Filtrative bleb: the incidence of the functional filtering bleb(86%)in experimental group was more than the one in control group(67%), there was significant different between the two groups(P<0.05). The incidence of complications of post-operation(shallow anterior chamber, choroidal detachment and bleb leaking)was lower than the one of the control group obviously.

CONCLUSION: Combined trabeculectomy with bio-amnion implantation can increase the rate of success and reduce the incidence of complications.