目的：观察中心性浆液性脉络膜视网膜病变(central serous chorioretinopathy，CSC)在频域光相干断层扫描(FD-OCT)中的图像特征，以及CSC患者外核层厚度与最佳矫正视力(BCVA)的关系。

方法：对确诊为CSC患者54例58眼和健康人30例60眼(对照组)行FD-OCT检查，采用Cirrus 3D-OCT模式对眼底黄斑部进行线性水平扫描。扫描深度1.9mm。扫描面积5.8mm×5.8mm，扫描模式512×496。观察CSC的FD-OCT图像特征，并测量不同时期CSC患者中央凹处外核层厚度，评估外核层厚度与BCVA的关系。

结果：所有54例58眼CSC患者OCT检查典型的形态改变，以单纯性神经上皮层脱离和神经上皮层脱离伴色素上皮层脱离为主，约84.5%。CSC患者黄斑中心凹处外核层的平均厚度在急性期最厚，随着病情的缓解，逐渐变薄，但恢复期仍较正常人厚； CSC患者的中心凹处外核层的厚度与BCVA呈负相关。

结论：FD-OCT能清楚地显示CSC的形态特征及病理形态学变化。CSC患者的中心凹处外核层的厚度与BCVA呈负相关。

AIM:To observe the imaging features of the foveal photoreceptor layer in eyes with central serous chorioretinopathy(CSC)using frequency-domain optical coherence tomography(FD-OCT)and to find the relationship between best-corrected visual acuity(BCVA)and the morphology of thickness of the outer nuclear layer.

METHODS: Totally 58 eyes from 54 CSC patients and 60 eyes from 30 healthy volunteers as the control group were selected. FD-OCT scan was performed on all the patients and volunteers. FD-OCT scan of 6mm horizontal line was performed, the scan depth was 1.9mm with a 5.8mm×5.8mm transverse area, the vertical and horizontal resolution was 5μm and 18μm respectively. The scan mode was 512×496. The morphological changes of FD-OCT on different stages of CSC were observed and the relationship between best-corrected visual acuity(BCVA)and the morphology of thickness of the outer nuclear layer were analyzed.

RESULTS: Simple serous neuroepithelial layer detachment and simple serous neuroepithelial layer detachment associated with pigment epithelial layer detachment at macula were about 84.5% of all the patients. Thickness of the outer nuclear layer was thinner from acute stage to chronic stage of CSC, and the relationship between thickness of the outer nuclear layer and BCVA was negative.

CONCLUSION: FD-OCT can detect the detailed morphologic changes and pathological morphology at the foveal photoreceptor layer in eyes with CSC patients.