方法：1型或2型糖尿病患者93例186眼，先后进行单视野免散瞳数码眼底照相、散瞳直接眼底镜检查和FFA，以FFA诊断结果作为比较标准，评价单视野免散瞳数码眼底照相和散瞳直接眼底镜筛查DR的敏感性和特异性。

结果：单视野免散瞳数码眼底照相检出DR的敏感性和特异性分别为80.4%和94.7%，而散瞳直接眼底镜检出DR的敏感性和特异性分别为64.2%和84.2%。当把筛查阈值下调至中度非增殖性DR(M-NPDR)后，单视野免散瞳数码眼底照相检出DR的敏感性和特异性分别提高为88.9%和98.4%，散瞳直接眼底镜检出DR的敏感性和特异性也均有提高，分别为71.5%和96.7%。

结论：单视野免散瞳数码眼底照相是筛查DR的有效工具。

METHODS:All 93 patients of type 1 or 2 diabetic who have underwent one-field non-mydriatic digital fundus photography, and direct ophthalmoscopy with dilation of their pupils, and FFA by ophthalmologists. The sensitivity and specificity of one-field non-mydriatic digital fundus photography and direct ophthalmoscopy were calculated respectively, compared with FFA.

RESULTS: The sensitivity and specificity of one-field non-mydriatic digital fundus photography for detection of any DR were 80.4% and 94.7%; The sensitivity and specificity of direct ophthalmoscopy for detection of any DR were 64.2% and 84.2%; After the standard for referable DR being lowered down to the moderate non-proliferative diabetic retinopathy(M-NPDR), the sensitivity and specificity of non-mydriatic digital fundus photography for detection were 88.9% and 98.4%, the sensitivity and specificity of direct ophthalmoscopy for detection were 71.5% and 96.7%.

CONCLUSION: One-field non-mydriatic digital fundus photography is an effective method for DR screening.