方法：POAG患者60例60眼，分别采用532nm倍频Q-开关Nd：YAG激光治疗仪，以光斑400μm，脉冲时间3ns，能量0.3～1.2mJ行180°和360°SLT。观察患者术后6mo的眼压变化。

结果：两组患者眼压在激光治疗后均有显著下降，180°组患者术前平均眼压为25.6±2.0mmHg(1kPa=7.5mmHg)，术后1h； 1d； 1wk； 1，3，6mo眼压分别为27.1±2.1，16.5±1.9，19.6±1.9，18.5±1.8，19.9±1.9，20.3±1.8mmHg。360°组患者术前平均眼压为25.4±2.1mmHg，术后对应时间点眼压分别为26.6±1.9，15.9±2.0，19.0±2.0，17.8±1.9，18.7±2.0，19.2±1.9mmHg。两组术后1d； 1wk； 1，3，6mo的眼压与术前相比明显下降，差异均有统计学意义(P<0.01)。术后两组各时间点眼压的平均下降幅度比较，360°组较180°组术后眼压的平均下降幅度更大，其中术后3mo和6mo差异具有统计学意义(P<0.05)。

结论：360°SLT治疗POAG的疗效可能优于180°SLT。

METHODS: Totally 60 cases(60 eyes)of POAG were treated by SLT with light spot diameter of 400μm, irradiation time of 3 nanosecond, and power of 0.3-1.2mJ. Patients were evaluated 1 hour, 1 day, 1 week, 1 month, 3 and 6 months after laser treatment.

RESULTS: Intraocular pressure(IOP)decreased significantly in two groups after laser treatment. The mean preoperative IOP was(25.6±2.0)mmHg(1kPa=7.5mmHg)in 180-degree SLT group, and(25.4±2.1)mmHg in 360-degree SLT group. The mean IOP at 1 hour, 1 day, 1 week, 1 months, 3 months and 6 months postoperatively were(27.1±2.1)mmHg,(16.5±1.9)mmHg,(19.6±1.9)mmHg,(18.5±1.8)mmHg,(19.9±1.9)mmHg,(20.3±1.8)mmHg, respectively, in 180-degree SLT group, and were(26.6±1.9)mmHg,(15.9±2.0)mmHg,(19.0±2.0)mmHg,(17.8±1.9)mmHg,(18.7±2.0)mmHg,(19.2±1.9)mmHg, respectively, in 360-degree SLT group. There were statistically significant decreases in IOP at 1 day, 1 week, 1 month, 3 months and 6 months postoperatively compared with preoperative IOP in the two groups(P<0.01). To compare the effect of two groups, the 360-degree SLT group showed significantly lower post-treatment IOP at each follow-up point relative to 360-degree SLT group, and its IOP reduction rate stayed statistically higher than the 180-degree group at 3 months and 6 months postoperatively(P<0.05).

CONCLUSION: This study suggests that 360-degree SLT is more effective than 180-degree SLT in treatment of POAG.