方法：对我院2005-03/2010-06药物治疗效果不显著、病灶位于角膜中、浅层的真菌性角膜炎患者168例，大于病灶边缘0.5mm角膜刀板层切除病变角膜至基本透明，角膜基质注射2g/L氟康唑至水肿区大于病变区切缘约0.5mm，依病灶大小自患眼就近取带蒂结膜瓣连续缝合覆盖植床。术后第1d常规开放点眼，并观察角膜感染有无复发，注射造成水肿消退情况，结膜植片血运及患眼刺激症状，及视力变化。

结果：患者157眼成功实施三联手术治疗，占拟实施此术式患者93.5%； 术后7d好转率96.2%，术后1mo，复发率3.8%，痊愈率95.5%，好转率0.6%； 注射药物后角膜基质水肿平均消退时间为13.4h； 术后1mo视力较术前提高者占24.8%，无明显变化者占58.0%，下降者占17.2%； 角膜内皮损失率0～8%，平均2.9%； 术后刺激症状：轻度87%，中度10%，重度3%； 住院天数平均7.3d； 住院费用平均2 160元； 术后3mo发现4例角膜轻微膨隆。

结论：角膜板层切除、氟康唑角膜基质注射、自体结膜移植三联术治疗早、中期真菌性角膜炎经济实用、疗效好、痊愈快，二期常规安全行光学性角膜移植术，对于经济条件差患者和角膜供体短缺地区，三联手术可作为首要选择。

METHODS: There were 168 cases suffered keratomycosis that the focus located shallow of the cornea and was not obvious to drug, who registered in our hospital from March 2005 to June 2010. In surgery we removed plate layer to cormea clear, the region was greater than focus for 0.5mm,then we injected fluconazole which is 2g/L density in corneal stroma to make the edema area greater than Removal of area for 0.5mm. At last we took pedicle conjunctival flap to cover the plant bed by continuous suture. Postoperative day use drug to drop eye and to observe that whether recurrent of the keratomycosis and how was the edema degrade, the blood supply of conjunctival graft pieces, how about the stimulating signs of the surgery eye, the vision.

RESULTS: The improvement rate was 96.2% after surgery for seven days and the cure rate was 95.5% after surgery for one months. We found in 157 eyes accepted trigeminy surgery there were 6 eyes recurrence and the recurrence rate was 3.8%. The mean time of corneal stromal edema faded away was 13.4 hours. After surgery for one month there were 39 eyes(24.8%)whose vision removed than preoperative, there were 91 eyes(58.0%)whose vision were same as preoperative and there were 27 eyes(17.2%)whose vision lower than preoperative. In these operations the loss ratio of corneal endothelium was from 0%-8%, the mean was 2.9%. The irritative symptoms postoperative were mild for 87%, moderate for 10% and severe for 3%. By this surgery the mean length of stay was 7.3 days so the mean hospitalization expenses only were 2160 RMB. Three months after surgery, 4 cases were slight corneal ectasia.

CONCLUSION: This operation combined corneal layer plate removal, Fluconazole injected corneal stroma and autologous conjunctival transplantation for keratomycosis which was in early-to-mid was affordable and curative effect. So which could be used in some district which shortage the cornea donor.