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[摘要]
目的：探讨直角边缘囊袋张力环(capsule tension ring，CTR)预防兔后囊膜混浊(posterior capsule opacification，PCO)的作用。
方法：新西兰兔20只随机分为两组，进行超声乳化晶状体摘除术后，实验组植入CTR 和Crane OV-55C 人工晶状体(intraocular lens，IOL)，对照组只植入Crane OV-55C IOL。观察术后并发症和PCO情况。术后3mo行光镜和透射电镜检查，观察晶状体后囊膜的形态学变化。
结果：术后3mo实验组和对照组都发生了明显的PCO(P>0.05)，各组Soemmering环形成程度无统计学差异(P>0.05)。病理学检查发现，两组兔赤道部晶状体上皮细胞增生形成了巨大的Soemmering环，大量晶状体上皮细胞移行至后囊膜。
结论：直角边缘CTR未能预防兔PCO的发生，有必要对其进一步改进。
[Key word]
[Abstract]
AIM: To evaluate the effect of sharp-edged capsule tension ring(CTR)on posterior capsule opacification(PCO).
METHODS: Twenty eyes of New Zealand white rabbits were randomly divided into two groups. After phacoemulsification, the experimental group was implanted with CTR and Crane OV-55C intraocular lens(IOL), and the control group was implanted with Crane OV-55C IOL only. Complications and PCO were observed by slit lamp microscope. Three months after surgery, light microscope and transmission electron microscope examinations were performed.
RESULTS: There was no statistically significant difference between the experimental group and the control group about PCO and Soemmering's ring formation(P>0.05). Pathological evaluations revealed lens epithelial cells(LECs)accumulated at the equatorial capsule forming a large Soemmering's ring and abundant LECs were migrated onto the posterior capsule forming a thick layer in both experimental group and the control group.
CONCLUSION: Sharp-edged CTR fail to retard PCO formation and development in rabbits and it is nessessary to improve it.
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