方法：回顾分析2010-06/2012-07行眼底荧光血管造影检查1 759例患者不良反应发生率及其处理方法。

结果：患者1 759例发生不良反应共267例，占15.17%； 其中恶心181例，占10.29%； 呕吐32例，占1.82%； 打喷嚏6例，占0.34%； 皮肤瘙痒及皮疹27例，占1.53%； 喉痒、咳嗽8例，占0.45%； 一过性心慌、胸闷8例，占0.45%； 头昏、头晕、胸闷、乏力、出冷汗5例，占0.28%。

结论：眼底荧光血管造影荧光素钠不良反应轻重不一，多数轻微，但在临床应用中应严格掌握适应证和禁忌证，对可能发生的严重反应做好及时救治的准备，以确保患者的生命安全。

METHODS:The incidence of side effects and corresponding treatments of 1 759 patients in fundus fluorescein angiography from June 2010 to July 2012 were reviewed and analyzed.

RESULTS:Totally, 267 out of 1759(15.17%)patients had side effects, nausea was reported in 181 cases(10.29%), vomiting in 32 cases(1.82%), sneezing in 6 cases(0.34%), itchy skin and rash in 27 cases(1.53%), itchy throat and cough in 8 cases(0.45%), a transient palpitation and chest tightness in 8 cases(0.45%), dizziness, chest tightness, fatigue and cold sweat in 5 cases(0.28%).

CONCLUSION: Fluorescein sodium injection can cause the side effects of varying severity, mostly minor side effects. However, indications and contraindications should be strictly controlled and preparation for severe side effects should be ready during treatment to ensure patient safety in case of emergency.