方法：选取我院眼科门诊2010-02/2012-12收治的86例糖尿病视网膜病变患者，利用随机数字表法进行分组，分别设为研究组和对照组，每组各43例。两组均采取常规降血糖和对症处理，其中研究组在此基础上给予葛根素进行治疗。记录两组患者在治疗前和治疗后1mo末的血流动力学和血液流变学情况，并做对比。

结果：(1)两组患者在治疗前的血液流变学指标差异不存在统计学意义(P>0.05)； 治疗后，研究组患者的血细胞压积、全血黏度低切、全血黏度高切、血浆黏度、红细胞聚集指数均低于对照组，差异有统计学意义(P<0.05)。(2)两组在治疗前的血流动力学指标差异不存在统计学意义(P>0.05)； 治疗后，研究组收缩期最大血流速度(PSV)、舒张末期血流速度(EDV)均高于对照组，研究组阻力指数(RI)低于对照组，差异有统计学意义(P<0.05)。

结论：葛根素能够改善糖尿病视网膜病变患者的血流动力学和血液流变学情况，并能保护视网膜中央动脉功能，进而可起到延缓和改善病情的效果。

METHODS: Eighty-six patients with diabetic retinopathy were selected in our hospital from February 2010 to December 2012. They were randomly divided into study group and control group, each group of 43 cases. The two groups were taken blood glucose and symptomatic treatment, while study group were given to puerarin based on the therapy. Recording two groups of patients in hemodynamics and blood rheology in 1 month before and after the treatment, and make a contrast.

RESULTS: Before treatment, the two group in blood rheology indexes, was not statistically significant(P>0.05); after treatment, patients in the study group of the hematocrit, the whole blood viscosity at low shear rate, plasma viscosity, whole blood viscosity, erythrocyte aggregation index were lower than those in the control group, the differences were statistically significant(P<0.05). Two groups had no statistically significant differences in the hemodynamic parameters before treatment(P>0.05); after treatment, Peak systolic velocity(PSV)and end diastolic velocity(EDV)in study group were higher than those in the control group, but the resistance index(RI)was lower than that in control group, the difference was statistically significant(P<0.05).

CONCLUSION: Puerarin can improve hemodynamics and hemorheology in patients with diabetic retinopathy, and can protect the central retinal artery function.