[关键词]
[摘要]
目的:探讨活血利水明目颗粒治疗超声乳化白内障术后角膜水肿的作用。
方法:将超声乳化白内障术后第1d发生2级以上角膜水肿的病例随机分为常规用药组与活血利水明目颗粒组,每组45例。常规用药组:给予妥布霉素地塞米松眼液、复方托吡卡胺眼液、重组牛碱性成纤维细胞生长因子眼液交替滴眼。活血利水明目颗粒组:在常规西药治疗的同时,加服具有活血利水、明目退翳功效的中药活血利水明目颗粒,观察两组患者的临床疗效与角膜水肿消退时间。1wk为1疗程,2个疗程结束时统计疗效。
结果:活血利水明目颗粒组的临床治愈率与角膜水肿平均消退时间均明显优于常规用药组(P均<0.05),总有效率与常规用药组比较无明显差异(P>0.05)。
结论:活血利水明目颗粒治疗超声乳化白内障术后角膜水肿具有较好的临床疗效,能缩短角膜水肿消退时间,提前恢复患者视力。
[Key word]
[Abstract]
AIM: To investigate the effects of Huoxuelishuimingmu Granules on corneal edema after phacoemulsification.
METHODS: Ninety cases with at least second degree corneal edema the first day after phacoemulsification were randomly divided into the routinely treated group and the Huoxuelishuimingmu Granules intervened group, 45 cases for each group. To the routinely treated group, Tobramycin and Dexamethasone Eye Drops, Compound Tropicamide Eye Drops and Recombinant Bovine Basic Fibroblast Growth Factor Eye Drops were administered in turn during the treatment. While to the Huoxuelishuimingmu Granules intervened group, traditional Chinese medicines with the function of promoting blood circulation, alleviating water retention and removing nebula named Huoxuelishuimingmu Granules were additionally administered. The curative effects and the time taken for vanishment of corneal edema in each group were then observed. One week was counted as a course of treatment and curative effects were calculated after two courses.
RESULTS: The Huoxuelishuimingmu Granules intervened group showed a much higher clinical cure rate and took quite shorter time for vanishment of corneal edema compared with the group treated with routine drugs(P<0.05 in both aspects), while no better total effective rate was observed(P>0.05).
CONCLUSION: Huoxuelishuimingmu Granules has a preferable clinical effect on corneal edema after phacoemulsification, shortening the duration of corneal edema and restoring the sight of patients in advance.
[中图分类号]
[基金项目]
泸州市科技局课题(No.泸市科\〖2011\〗108号)