方法：选取屈光参差性单眼弱视青少年31例，利用OCT技术分别检测双眼黄斑视网膜厚度和容积，比较同一受检者弱视眼与非弱视眼的差异。并用A超测量眼轴长度，分析黄斑厚度、黄斑容积与眼轴的关系。

结果：弱视眼黄斑中心凹1mm区域及鼻侧内圈厚度比正常眼厚(P=0.0358，0.0003)，而黄斑部位其它分区厚度及黄斑总容积弱视眼和正常眼相比差异均无统计学意义(P>0.05)。不同程度弱视患者间黄斑各参数差异均无统计学意义(P>0.05)。弱视眼及非弱视眼黄斑参数与眼轴之间无明显相关性。

结论：屈光参差性单眼弱视青少年弱视眼黄斑的组织结构上存在一定差异。

METHODS: Thirty-one juveniles with unilateral anisometropic amblyopia were selected. Macular retinal thickness and macular volume were measured by OCT with both eyes in all participants, and the differences between amblyopic eyes and non-amblyopic eyes were compared. Axial length(AL)was measured by A-ultrasound. The relationship between AL and the factors of macula was analyzed.

RESULTS: The central sector region and the nasal inner region in amblyopic eyes were thicker than those in normal eyes(P=0.0358, 0.0003), but there was no significant difference in any other region between amblyopic eyes and normal eyes(P>0.05). No significant difference was found in macular volume between amblyopic eyes and normal eyes(P>0.05). The factors of the macula in both eyes were not significantly related to the AL.

CONCLUSION: There exists some difference in structure of macula between amblyopic eyes and non-amblyopic eyes in adolescent with unilateral anisometropic amblyopia.