Retinopathy of prematurity(ROP)is a disease of retinal vascular proliferative lesions which occurs in premature and low birth weight infants. The incidence is increasing in view of the rising numbers of preterm deliveries and improved neonatal care. Traditional modalities of treatment include cryotherapy and laser therapy, which are laborious and require special training. Hence, research is on the way to find novel treatment modalities used for early stage of the disease with the characteristics of easy operation, safety and efficacy. We reviewed the published and unpublished literature on newer methods of ROP management.