方法：选取2012-01/06来我院就诊的DR患者104例180眼做为研究对象，采用随机数字表法将其分为三组：药物治疗组(32例56眼)和激光治疗组(50例86眼)及联合治疗组(22例38眼)，分别给予药物治疗、577nm激光治疗、药物治疗联合577nm激光治疗，随访6mo后，对比患者在治疗前后视力及眼底的改善程度。

结果：激光治疗组的视力改善程度明显高于药物治疗组， 眼底毛细血管无灌注区消失及新生血管消退率高于药物治疗组，差异均有统计学意义(P<0.05)； 联合治疗组效果好于单因素治疗组，差异均有统计学意义(P<0.05)。

结论：577nm激光联合联合羟苯磺酸钙治疗DR的疗效确切，值得在临床更多应用。

METHODS: From January 2012 to June 2012, 104 patients(180 eyes)with diabetic retinopathy were selected and randomly divided into medicine group, 577-nm laser group and combined treatment group. The medicine group consisting of 32 cases(56 eyes)received calcium dobesilate, and 577-nm laser group including 50 cases(86 eyes)were treated by photocoagulation with 577-nm laser. And 22 cases(38 eyes)of combined treatment group were treated with both methods above. The follow-up period was 6mo. The effects were evaluated by visual acuity and fundus fluorescein angiography(FFA).

RESULTS: Compared with medicine group, the rate of disappeared retinal capillary nonperfusion areas and regressed neovascularization was higher in 577-nm laser group. And the visual acuity of 577-nm laser group was improved significantly more than the medicine group. The difference was statistically significant(P<0.05). The combined treatment group achieved more favorable results than every single treatment group(P<0.05).

CONCLUSION: Photocoagulation with 577-nm laser combined with calcium dobesilate is effective for diabetic retinopathy and it is worth making more application in clinic.