[关键词]
[摘要]
目的：探讨Behcet病(Behcet's disease，BD)患者血清TNF-α、IFN-γ、MCP-1的水平。
方法：BD患者25例，对照组为健康志愿献血员30例，抽取血清检测TNF-α、IFN-γ、MCP-1等指标。
结果：BD活动期患者TNF-α、IFN-γ、MCP-1均高于健康对照组，差异有统计学意义。
结论：BD活动期患者TNF-α、IFN-γ、MCP-1异常升高，可能与BD的发病机制有关。
[Key word]
[Abstract]
AIM: To study the serum levels of TNF-α, IFN-γ and MCP-1 in patients with Behcet's disease(BD).
METHOS: Twenty-five patients with BD as study group and 30 normal volunteers as control group were inclued in the study. Serum levels of TNF-α, IFN-γ and MCP-1 were measured.
RESULTS: Serum levels of TNF-α, IFN-γ and MCP-1 were significant higher in active BD patients than in normal controls.
CONCLUSION: Our results suggest that serum levels of TNF-α, IFN-γ and MCP-1 abnormally increased in active BD paiteins. The higher expression may play a role in the pathogenesis of BD.
[中图分类号]
[基金项目]
广州市中医药科技项目(No. 20132A011014)
