[关键词]
[摘要]
目的:观察分析青光眼患者血流变、Aβ、β-EP、Hcy及眼部血流动力学指标的变化情况。
方法:选取2011-11/2013-10本院收治的60例青光眼患者为观察组,并以60例健康人员为对照组,然后将两组的血流变、Aβ、β-EP、Hcy及眼部血流动力学指标进行检测与比较,同时对不同Richardson分期者的检测水平进行比较。
结果:观察组的血流变、同型半胱氨酸(Hcy)、β淀粉样蛋白(Aβ)、β内啡肽(β-EP)及血管阻力指数(RI)均显著地高于对照组,PSV及EDV则均明显地低于对照组,且其中Richardson分期较高者的波动大于Richardson分期较低者,P均<0.05,上述比较指标均有显著性差异。
结论:青光眼患者血流变、Aβ、β-EP、Hcy及眼部血流动力学指标的变化较大,并且分期较高者的血供较差及血清相关指标较高。
[Key word]
[Abstract]
AIM: To observe and analyze the change situation of hemorheology, Aβ, β-EP, Hcy and ocular hemodynamics indexes of patients with glaucoma.
METHODS: Sixty patients with glaucoma in our hospital from November 2011 to October 2013 were the observation group, 60 healthy people were the control group, then the hemorheology, Aβ, β-EP, Hcy and ocular hemodynamics indexes of two groups were detected and compared, then the detection levels of patients with different Richardson stages were compared.
RESULTS: The hemorheology, Aβ, β-EP, Hcy and RI of observation group were all significantly higher than those of control group, and the PSV and EDV were obviously lower than those of control group, the fluctuation of patients with higher Richardson stages were all bigger than those of patients with lower Richardson stages,all P<0.05, there were all significant differences between those comparison indexes.
CONCLUSION: The change of hemorheology, Aβ, β-EP, Hcy and ocular hemodynamics indexes of patients with glaucoma are great, and the blood supply of patients with higher stages are worse, and the serum related indexes were higher.
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