方法：回顾性分析2011-01/2013-06于我院行穿透性角膜移植术的患者150例150眼。

结果：病因：角膜白斑99眼(66%)，角膜变性18眼(12%)，角膜溃疡15眼(10%)，角膜内皮失代偿10眼(6.7%)，圆锥角膜8眼(5.3%)。疗效：植片透明110例(73.3%)。视力≤0.05者42例(28%)，0.05<视力≤0.3者60例(40%)，视力>0.3者48例(32%)。并发症：主要并发症为免疫排斥反应28例(18.7%)。

结论：穿透性角膜移植是治疗角膜疾病致盲的重要有效手段，但术后排斥反应仍是影响手术成功的主要因素。

METHOTS: Retrospective analysis on 150 cases(150 eyes)of penetrating keratoplasty was done from Jan.2011 to June 2013.

RESULTS: Reasons: coneal lecuma 99 eyes(66%); corneal degeneration 18 eyes(12%); corneal ulcers 15 eyes(10%); corneal endothelium decompensation 10 eyes(6.7%); keratoconus 8 eyes(5.3%). Effects: Grafts were transparent in 110 eyes(73.3%). There are 42 eyes(28%)less than or equal to 0.05 in visual acuity,60 eyes(40%)better than 0.05 and less than or equal to 0.3 and 48 eyes(32%)better than 0.3. Complication: The main complication was immune rejection(28 eyes, 18.7%).

CONCLUSION: Penetrating keratoplasty is an important and effective means for keratitis disease.