方法：在规范的验光条件下配镜，矫正处方分渐变镜组、欠矫组、全矫组，戴镜治疗弱视。收入随访期满24mo，资料完整病例270例540眼。观察低度远视、中度远视、高度远视引起的双眼屈光不正性弱视的治愈率与平均治愈时间。

结果：低度远视引起的弱视，三种矫正方法2a治愈率无统计学意义。三种矫正方法平均治愈时间分别为渐变镜组(7.33±2.11mo)； 欠矫组(9.0±3.71mo)； 全矫组(12.5±5.17mo)。三组样本经t检验显示：渐变镜组与欠矫组(t=1.66，P>0.05)无统计学意义； 渐变镜组与全矫组(t=3.92，P<0.01)有统计学意义； 欠矫组与全矫组(t=2.33，P<0.05)有统计学意义。中度远视引起的弱视，三种矫正方法2a治愈率，三组比较差异有统计学意义(χ²=6.75； P<0.05)，渐变镜组与欠矫组，渐变镜组与全矫组的比较，差异有统计学意义(χ²=6.3，P<0.01； χ²=8.1，P<0.05)。三种矫正方法的疗效治愈时间分别为渐变镜组(14.0±4.87mo)； 欠矫组(16.93±4.58mo)； 全矫组(17.93±4.42mo)。经t检验显示：渐变镜组与欠矫组(t=2.88，P<0.01)﹑渐变镜组与全矫组(t=3.9，P<0.01)有统计学意义，欠矫组与全矫组(t=1.01，P>0.05)无统计学意义。高度远视引起的弱视，三种矫正方法2a治愈率无统计学意义(χ²=2.43，P>0.05)。三组治愈时间比较差异无统计学意义(t=1.49，P>0.05； t=1.46，P>0.05； t=1.11，P>0.05)。

结论：在规范的验光条件下，渐变多焦镜的应用，为弱视患儿的治疗，提供了一种全新有效的治疗方式，弥补了全矫与欠矫在临床治疗上的不足。

METHODS: This study included 270 cases(54 eyes)with complete data, and followed up 24mo. All the amblyopic children were given standard prescription and were divided into progressive addition glass group, under corrected group and full corrected group. And all were observed for their therapy effect and the average healing time in low hyperopic, moderate hyperopic and high hyperopic children with ametropic amblyopia respectively.

RESULTS: In low hyperopic children, the difference of the therapy effect of the three corrected methods were insignificant in two years. The meam cure time of the three corrected methods were(7.33±2.11)mo in progressive addition glass group;(9.0±3.71)mo in under corrected grope;(12.5±5.17)mo in full corrected group. Three groups of independent samples by paired t-test showed: the difference between progressive addition glass group and under corrected grope(t=1.66, P>0.05)was statistically insignificant; the difference between progressive addition glass group and full corrected grope(t=3.92, P<0.01)was statistically significant; the difference between under corrected grope and full corrected grope(t=2.33, P<0.05)was statistically significant. In moderate hyperopic chileren, the differences of the therapy effect of the three corrected methods were significant in two years(χ²=6.75; P<0.05). The difference between progressive addition glass group and under corrected grope(χ²=6.3; P<0.01)was statistically significant; the difference between progressive addition glass group and full corrected grope(χ²=8.1; P<0.005)was statistically significant. The mean cure time of the three corrected methods were(14.0±4.87)mo in progressive addition glass group;(16.93±4.58)mo in under corrected grope;(17.93±4.42)mo in full corrected group. Three groups of independent samples by paired t-test showed: the difference between progressive addition glass group and under corrected grope(t=2.88, P<0.01)was statistically significant; the difference between progressive addition glass group and full corrected grope(t=3.9, P<0.01)was statistically significant; the difference between under corrected grope and full corrected grope(t=1.01, P>0.05)was statistically insignificant. In high hyperopic amblyopic children, the difference of the therapy effect and the healing time of the three corrected methods were insignificant in two years.(χ²=2.43, P>0.05. t=1.49, P>0.05; t=1.46,P>0.05; t=1.11, P>0.05).

CONCLUSION: Under standard prescription, application of progressive multifocal glasses provides a new effective treatment for ametropic amblyopia in hyperopic children, and makes up the deficiency of the whole straightening and under correction in clinical treatment.