[关键词]
[摘要]
目的:期望能找到更好治疗眼碱烧伤,减少病患痛苦,减轻社会负担的方法。
方法:选择眼碱烧伤患者100例。根据化学烧伤程度分级分为4大组,每大组再随机分为对照组和治疗组各约一半。对照组行常规治疗,治疗组在观察组的基础上加用灯盏花素注射液40mg静滴。观察两组角膜恢复时间、视力变化、角膜混浊程度、角膜新生血管数量、其它并发症等。统计分析其疗效。
结果:治疗四大组患者中Ⅰ级的治疗组与对照组各项指标对比无显著性差异(P>0.05),Ⅱ,Ⅲ,Ⅳ级的各项指标对比均有显著性差异(P<0.05)。其角膜混浊程度与新生血管数量对比,治疗组明显优于对照组(P<0.05)。
结论:灯盏花素治疗眼碱烧伤能缩短疗程,减少角膜瘢痕,提高视力。
[Key word]
[Abstract]
AIM: To find better ways of treating ocular alkali burn, and to reduce the suffering of patients and social burden.
METHODS:Totally 100 patients were graded according to the degree of chemical burns to four major groups, each half were randomly divided into the control group and the treatment group. Control group underwent conventional treatment. In addition to conventional therapy, patients in each treatment group were also added a Breviscapine intravenous injection of 40mg daily. Corneal recovery time, changes in vision, degree of corneal opacity, number of corneal neovascularization and other complications were observed. Curative effects were analyzed statistically.
RESULTS: There was no significant difference in level Ⅰ group between control group and treatment group(P>0.05); There were significantly different in level Ⅱ, Ⅲ and Ⅳ group(P<0.05). Compared to the degree of corneal opacity and the number of corneal neovascularization, the treatment group was obviously better than the control group(P<0.05).
CONCLUSION: Breviscapine in the treatment of ocular alkali burns can shorten the course of treatment, reduce corneal scarring, and improve vision.
[中图分类号]
[基金项目]
中国深圳市坪山新区卫生系统科研孵化资金资助项目(No.2012-11)