方法：选择2012-01/2013-06在我院接受白内障超声乳化联合人工晶状体植入术的年龄相关性白内障患者90例90眼，随机分为两组：2.2mm切口组45例45眼，3.0mm切口组45例45眼，分别行2.2mm或3.0mm透明角膜隧道切口同轴白内障超声乳化术。术后1d； 1wk； 1，3mo随访，观察视力、角膜内皮细胞计数、中央角膜厚度、手术源性散光。

结果：术后1d，2.2mm切口组视力明显提高，差异有统计学意义(P<0.05)，术后1wk； 1，3mo，两组比较无统计差异。两组角膜内皮细胞计数、中央角膜厚度在术后1d； 1wk； 1，3mo均无统计学差异(P>0.05)。两组手术源性散光在术后1d； 1wk； 1，3mo均有统计学差异(P<0.05)，2.2mm切口组手术源性散光明显减小。

结论：2.2mm微小切口同轴白内障超声乳化术术后早期提高视力更明显，能明显减少手术源性散光，安全性更高。

METHODS: Patients with age-related cataract(90 cases, 90 eyes)were enrolled in the study from January 2012 to June 2013 in our hospital, and they were randomly divided into 2 groups: 2.2mm incision group(45 eyes of 45 cases), 3.0mm incision group(45 eyes of 45 cases). Corneal tunnel incision coaxial phacoemulsification was performed. At 1d, 1wk, 1, 3mo after operation, the visual acuity, corneal endothelial cell count, central corneal thickness, operation astigmatism were recorded.

RESULTS: One day after operation, the visual acuity of 2.2mm incision group were significantly improved, the difference was statistically significant(P<0.05), there were no differences in two groups at 1wk, 1, 3mo after operation. No significant differences between the two groups of corneal endothelial cell counting, central corneal thickness at 1wk, 1, 3mo after operation were observed(P>0.05). Operation source astigmatism had statistically significant difference at 1d, 1wk, 1, 3mo after operation(P<0.05), it decreased significantly in the 2.2mm incision group.

CONCLUSION: The 2.2mm small incision coaxial phacoemulsification with postoperative visual acuity improved more significantly, can significantly reduce the operation astigmatism.