目的：评估一种最新的光学低相干反射测量仪(Lenstar LS900^®； version 1.10)对学龄儿童的眼球生物测量结果的重复性，将其测量值与光学相干生物测量仪(IOL Master^®； 500 version 7.1)的测量结果进行比较。

方法：前瞻性观察比较分别由Lenstar和IOL Master测量的每个受检者右眼的眼球生物学参数。使用变异系数(coefficient of variation，CV)评价Lenstar测量结果的重复性，应用Bland-Altman图对Lenstar和IOL Master的测量数据进行一致性评价。

结果：本研究纳入了110个健康的学龄儿童，平均年龄10.9±2.0岁(年龄6～15岁)，54.5% 为女性。 Lenstar测量结果的重复性很高，其中眼轴长度(axial length， AL)的CV值最小(CV<0.1%)。Lenstar与IOL Master的测量结果比较，AL(23.90±1.28 vs 23.88±1.27mm， P<0.001)，前房深度(anterior chamber depth， ACD)(3.62±0.26 vs 3.58±0.25mm， P<0.001)和最大屈光力主子午线上角膜曲率半径CR2(7.58±0.27 vs 7.56±0.27mm， P<0.001)均略长。Lenstar和IOL Master测量数据的95%的一致性界限(limits of agreement， LoA)从小到大依次为-0.025至0.053mm(AL)，-0.047至0.057mm(最小屈光力主子午线上角膜曲率半径CR1)，-0.057至0.102mm(CR2)和-0.083至0.152mm(ACD)。

结论：对于学龄儿童，Lenstar可提供重复性很好的眼球生物测量数据(包括AL、ACD和角膜曲率测量值)，这些数据与IOL Master的测量结果之间具有很好的一致性。

AIM: To evaluate the repeatability of ocular biometrical measurements obtained from the optical low-coherence reflectometry(Lenstar LS900^® version 1.10), as well as its agreement with the partial coherence interferometry(IOL Master^® 500 version 7.1)in Chinese school-aged children.

METHODS: A prospective comparison of ocular biometrical measurements made by the Lenstar and IOL Master was performed on right eye of each participant. The intraobserver repeatability of Lenstar was assessed by coefficient of variation(CV). Agreement was analyzed using Bland-Altman plots.

RESULTS: The mean age of the 110 subjects(range 6-15y)was 10.9±2.0y, and 54.5% were female. The Lenstar yielded repeatable measurements, with the smallest CV was obtained for axial length(AL)(CV<0.1%). The Lenstar produced a greater mean value for AL(23.90±1.28 vs 23.88±1.27mm, P<0.001), anterior chamber depth(ACD)(3.62±0.26 vs 3.58±0.25mm, P<0.001), and the steepest corneal radius of curvature(CR2)(7.58±0.27 vs 7.56±0.27mm, P<0.001)than IOL Master. The 95% limits of agreement(LoA)between the two instruments were -0.025 to 0.053mm for AL, -0.047 to 0.057mm for the flattest corneal radius of curvature(CR1), -0.057 to 0.102mm for CR2, and -0.083 to 0.152mm for ACD.

CONCLUSIONS: The Lenstar yielded excellent repeatability results of AL, ACD, and corneal curvature measurements, which were interchangeable with the IOL Master measurements in school-aged children.