目的：探讨睑板腺功能障碍(meibomian gland dysfunction，MGD)患者的诊疗方法，为临床治疗提供依据。方法：回顾性分析2012-07/2014-06在长江大学附属第一医院眼科门诊诊治的MGD患者96例192眼，裂隙灯显微镜下进行睑缘形态和功能的检查、泪膜破裂时间(BUT)、泪液分泌试验(SⅠt)检查，并进行清洁睑缘、睑板腺按摩、挤压睑板、人工泪液及抗生素和激素等综合治疗。结果：睑缘、睑脂排出情况平均评分分别为3.02±0.78，1.90±0.76。所有患者BUT均异常，平均为4.3±1.9s； 84眼SⅠt正常，32眼5mm/5min<<SⅠt≤10mm/5min，76眼≤5mm/5min，平均为7.9±4.4mm/5min； 经治疗愈后良好，总有效率达90.6%。结论：MGD患者可引起干眼常见症状，通过睑板腺裂隙灯检查、BUT及SⅠt检查，可对患者进行及时、准确的诊断和积极治疗。

AIM: To study the detective methods in meibomian gland dysfunction(MGD)and provide the evidences for the diagnosis and treatment.METHODS: The clinical data of 96 MGD patients(192 eyes)from July 2012 to June 2014 in Departmetn of Ophthalmology, the First Affiliated Hospital of Yangtze University were retrospectively analyzed. The patients were detected by eyelid rims, slit lamp microscope, tear-film breakup time(BUT)and Schirmer I test(SⅠt). And they were comprehensively treated by eyelid rims cleaning, meibomian gland massages, squeezing tarsus, artificial tears, antibiotics and hormones.RESULTS: The average score of eyelid rims and the outflow of palpebral sebum respectively was 3.02±0.78, 1.90±0.76. The BUTs were abnormal in all patients, the average score of BUT was 4.3±1.9s; The S I t of 84 eyes were normal, that of 32 eyes were 5mm/5min <SIt≤10mm/5min, 76 eyes were≤5mm/5min, the average SⅠt score was 7.9±4.4mm/5min. The prognosis were good, the total effective rate was 90.6%.
CONCLUSION: The patients of MGD always cause some dry eye syndromes. We should timely and accurately diagnose and treat the MGD patients with eyelid rims, slit lamp microscope, BUT and SⅠt.