方法：干眼症儿童100例200眼被随机平均分为对照组和试验组，对照组用1g/L玻璃酸钠滴眼液4次/d，试验组用小牛血去蛋白提取物眼用凝胶4次/d； 两组同时去除病因治疗。对比分析治疗前与治疗后30d的症状评分、Schirmer Ⅰ、泪膜破裂时间(BUT)、角膜荧光素染色评分。

结果：各组治疗前后各项评分比较有统计学意义(P<0.05)； 两组治疗后各项评分比较有统计学意义(P<0.05)。

结论：小牛血去蛋白提取物眼用凝胶能有效治疗儿童干眼症。

METHODS: One hundred patients(50 patients each group)with children dry eye were divided into two groups randomly: control group was dropped 1g/L sodium hyaluronate eye drop four times per day and experimental group was dropped protein-free calf blood extract ophthalmic gel four times per day. Both groups received the depathogeny treatment at the same time. Symptom scores, Schirmer I test values, tear break-up time(BUT), cornea fluorescein staining scores were recorded on the prior treatment and 30d post-treatment, then they were analyzed.

RESULTS: There were statistically significant difference(P<0.05)for the comparison in the symptom scores, Schirmer I test values, BUT, cornea fluorescein staining scores of prior treatment and post-treatment in each groups. And there were statistically significant difference(P<0.05)in the same items of post-treatment between the two groups.

CONCLUSION: There is a clearly beneficial effect of protein-free calf blood extract ophthalmic gel on healing children dry eye.