方法：选择本院睑板腺功能障碍性干眼患者86例172眼，给予泪膜破裂时间测定、角膜染色及分级，以及通过红外线睑板腺分析仪、睑板腺挤压试验，分别观察睑板腺腺体缺失评分及睑板腺分泌物性状评分等方法明确诊断后，在不同阶段采取综合治疗后(综合治疗包括清洁、热敷、按摩联合妥布霉素地塞米松眼液、普拉洛芬滴眼液和聚乙二醇滴眼液等)，对其治疗的有效性进行评定分析。

结果：对86例172眼患者经治疗3wk时进行观察，其中46例92眼治愈， 29例58眼有效， 11例22眼无效，总有效率87.2%。治疗6wk时观察，其中68例136眼治愈， 13例26眼有效， 5例10眼无效，总有效率94.2%，治疗过程中未出现眼部及全身不良反应。

结论：采取综合治疗睑板腺功能障碍性干眼，可有效缩短病程，快速解除睑板腺管阻塞，恢复睑板腺分泌功能及泪膜脂质层的稳定性，积极有效的减轻了患者干眼症状的不适感。

METHODS:Totally, 86 cases(172 eyes)in our hospital, who suffered from meibomian gland dysfunctional dry eye, were measured by BUT, CFS, the machine of infrared meibomian gland function and testing meibomian gland after extrusion. The scores of meibomian gland function missing and secretions were observed, which as a diagnosis, and assessed the effectiveness of treatment, after took comprehensive treatments in different stages(comprehensive treatments including cleaning, hot covering, massaging, TobraDex, Pranoprofen and Lubricant, etc.).

RESULTS:All patients were treated and observed for 3wk, in which 46 cases(92 eyes)of cured, 29 cases(58 eyes)effective, 11 cases(22 eyes)ineffective, the total effective rate was 87.2%. After 6wk, 68 cases(136 eyes)of cured, 13 cases(26 eyes)effective, 5 cases(10 eyes)ineffective, the total effective rate was 94.2%, not appeared adverse ocular and systemic reactions in the process of treatment.

CONCLUSION: Taken comprehensive treatments for meibomian gland dysfunctional dry eye could effectively shorten the course of the disease, quickly remove meibomian gland tube obstruction, restore the meibomian gland secretion and stable the lipid layer, and could reduce the discomfort of patients with dry eye positively and effectively.