方法：将60例87眼干眼症患者随机地分为对照组与观察组，分别为42眼与45眼。对照组采用硫酸软骨素滴眼液治疗，观察组采用金因舒治疗。比较两组临床疗效、治疗前后相关指标(症状评分、BUT，SⅠt，FL)变化情况、治疗后生活质量及不良反应发生情况。

结果：对照组临床总有效率为71%，显著低于观察组(91%)，差异具有统计学意义(P<0.05)； 两组治疗前后症状评分、BUT，SⅠt及FL水平差异均具有统计学意义(P<0.05)，且两组治疗后上述指标差异也均具有统计学意义(P<0.05)； 观察组治疗后生活质量评分为142.16±10.32分，显著高于对照组治疗后115.24±7.34分，差异具有统计学意义(P<0.05)； 对照组不良反应发生率为13%，观察组为10%，差异无统计学意义(P>0.05)。

结论：金因舒治疗干眼症疗效显著，其治疗干眼效果优于硫酸软骨素。

METHODS:Sixty cases(87 eyes)of dry eye patients were randomly divided into control group and observation group, 42 eyes and 45 eyes respectively. The control group received Chondroitin sulfate eye drops treatment, and the observation group were used for treatment of Jinyinshu. The changes of clinical efficacy, correlation index(symptom score, BUT, S I t, FL)before and after treatment, quality of life after treatment and the incidence of adverse reactions were compared.

RESULTS: In the control group, the total clinical effective rate was 71%, which was significantly lower than that in the observation group(91%), the difference was statistically significant(P<0.05); There were statistical differences of symptom scores, BUT, SⅠt and FL level of the two groups before and after treatment(P<0.05), and there were statistical differences of the above indexes after treatment between the two groups(P<0.05); The quality of life score was 142.16±10.32 of the observation group after treatment, which was significantly higher than that in the control group after treatment(115.24±7.34), the difference was statistically significant(P<0.05); The incidence of adverse reaction of the control group was 13%, 10% in the observation group, and there were no statistical differences(P>0.05).

CONCLUSION: Jinyinshu is significantly effective in the treatment of dry eye, and its clinical efficacy is better than chondroitin sulfate.