方法：选择2010-01/2012-02于沈阳市第四医院眼科接受femto-LASIK术(A组)或LASIK术(B组)的近视及近视散光患者各80例80眼，近视度数在-1.50～-10.00D，散光度≤-6.0D，矫正视力≥1.0的患者，跟踪随访6mo，常规记录裸眼视力、最佳矫正视力、客观验光值、裂隙灯检查、术后有无并发症、眼压、角膜地形图等，术前术后行明环境下和暗环境下CS检查，比较两组明暗环境下CS的变化。

结果：研究对象160例中，所有患者手术均成功，femto-LASIK术组(A组)术后明暗环境下各空间频率的CS均高于标准LASIK术组(B组)。其中A组术后1mo明视CS、术后3mo暗视CS均恢复至术前水平，术后6mo时均较术前提高； B组术后3mo明视CS达术前水平，暗视CS术后6mo时仍没恢复至术前水平。

结论：femto-LASIK术矫正近视和近视散光，在提高术后明暗环境下CS比标准LASIK术更有优势。

METHODS: In a prospective study 160 myopia and myopic astigmatism patients' eyes were involved, which accepted femto-LASIK or LASIK in our hospital from January 2010 to February 2012. The myopia degree was -1.50～-10.00D, the astigmatism degree ≤-6.0D. Eighty eyes were treated with femto-LASIK in group A, and 80 eyes were treated with LASIK in group B, All patients in the treatment group completed the final 6mo of follow-up. The uncorrected visual acuity(UCVA)and the best spectacle-corrected visual acuity(BSCVA), objective and manifest refractions, results of slit-lamp examination, the side effects, intraocular pressure, corneal topography, CS in photopic and scotopic environments were noted.

RESULTS: All of operations on 160 cases were successful without severe complication after 6 mo follow-up. CS of femto-LASIK group(group A)at each spatial frequency environment were higher than that of LASIK group(group B). In group A, after 1mo the photopic CS, after 3mo of scotopic CS recovered to the preoperative level, 6mo after surgery improved than before the operation. In group B, after 3mo photopic CS to the preoperative level, scotopic CS at 6mo after operation was still not recovered to the preoperative level.

CONCLUSION:Femto-LASIK for correction of myopia and myopic astigmatism, in improving the postoperative contrast sensitivity under shade environment has more advantages than LASIK.