方法：收集2014-01/04在潍坊眼科医院行飞秒激光制瓣的准分子激光原位角膜磨镶术(FS-LASIK)及机械板层刀制瓣准分子激光原位角膜磨镶术(LASIK)的患者60例120眼，年龄27.46±6.65岁。其中LASIK组28例56眼，FS-LASIK组32例64眼。应用Oculus干眼分析仪观察患者术前、术后1wk及术后1mo时泪河高度、首次泪膜破裂时间、平均泪膜破裂时间随时间的变化。

结果：Oculus干眼分析仪检查术前泪河高度为0.25±0.10mm，首次泪膜破裂时间为6.70±3.86s，平均泪膜破裂时间为10.14±4.51s。术后1wk泪河高度为0.19±0.04mm，首次泪膜破裂时间为4.87±1.71s，平均泪膜破裂时间为7.77±2.30s， 两组患者术后1wk与术前相比差异有统计学意义(P<0.05)。术后1mo泪河高度为0.19±0.18mm，平均泪膜破裂时间为8.72±2.54s，首次泪膜破裂时间为5.02±2.30s，两组患者术后1mo与术前相比差异有统计学意义(P<0.05)。两组患者术后1mo与术后1wk泪河高度及平均泪膜破裂时间差异均有统计学意义。术后1mo首次泪膜破裂时间与术后1wk相比差异无统计学意义。FS-LASIK与LASIK组组间比较，差异无统计学意义(P>0.05)。

结论：机械板层刀制瓣LASIK和FS-LASIK术后患者均有不同程度的干眼，泪液分泌量及泪膜的稳定性均有不同程度的下降，加用人工泪液干眼症状有所改善。Oculus干眼分析仪非侵入性的反映泪液量及泪膜稳定性，有利于LASIK术后干眼的快速诊断及严重程度的判断。

METHODS: The people who had femtosecond LASIK(FS-LASIK)and mechanical microkeratome LASIK in Weifang Eye Hospital from January 2014 to April 2014 were observed. Sixty patients(120 eyes)who had corneal refractive surgery were collected. The average age of patients was 27.46±6.65 years old. The LASIK group had 28 patients(56 eyes)and the FS-LASIK group had 32 patients(64 eyes). The tears river altitude, first tear break up time(BUT), and average BUT at preoperative, 1wk and 1mo after operation were observed by Oculus dry eye analyzer.

RESULTS: By Oculus dry eye analyzer examination, the preoperative tears river altitude of patients was 0.25±0.10mm. First BUT was 6.70±3.86s. Average BUT time was 10.14±4.51s. At 1wk after operation, the tears river altitude of patients was 0.19±0.04mm. The first BUT time was 4.87±1.71s. The average BUT time was 7.77±2.30s. There was significant difference between preoperative and 1wk after operation(P<0.05). At 1mo after operation in two groups, the tears river altitude of patients was 0.19±0.18mm.The average BUT 8.72±2.54s. The BUT was 5.02±2.30s. There was significant difference between preoperative and 1mo after operation(P<0.05). The two groups had significant difference in average tears river altitude and average BUT between 1mo and 1wk after operation. There was no significant difference in the first BUT between 1mo and 1wk after operation. There was no significant difference between LASIK and FS-LASIK groups at any time of the test(P<0.05).

CONCLUSION: LASIK and FS-LASIK patients have different degree of dry eye symptom after operation. Dry eye symptoms mainly display in the decrease of tear production and the stability of tear film. It will be better after giving artificial tears. Oculus dry eye analyzer is a non-invasive examination equipment. It can reflect the amount of tears and the stability of tear film. It is usefull in rapid diagnosis of dry eye and judgment of the degree of dry eye symptom after LASIK operation.