[关键词]
[摘要]
目的：比较复发性翼状胬肉切除手术联合角膜缘干细胞移植术术中使用不同浓度丝裂霉素治疗复发性翼状胬肉的临床疗效。
方法：将复发性翼状胬肉患者60例65眼随机分为三组，手术均采取角膜缘干细胞移植术，术中分别采用0.15g/L丝裂霉素21例22眼，采用0.25g/L丝裂霉素20例22眼，采用0.4g/L丝裂霉素19例21眼，治疗术后随访6mo～2a。
结果：三组复发率分别为9%，5%，5%，三组比较无显著性差异(P>0.05)，三组并发症发生率分别为5%，36%，33%，三组比较有显著性差异(P<0.05)。
结论：0.15g/L，0.25g/L和0.4g/L浓度丝裂霉素治疗复发性翼状胬肉复发率相似，但并发症0.15g/L浓度组发生率更低，是一种理想的手术方法值得推广应用。
[Key word]
[Abstract]
AIM: To compare the clinical efficacy of treatment on recurrent pterygium using different concentration mitomycin C(MMC)in the pterygium excision operation combined with the corneal limbal stem cell autografting(CLSCA).
METHODS: Sixty patients(65 eyes)with recurrent pterygium were randomly divided into three groups. All cases were accepted CLSCA, 21 patients(22 eyes)were given 0.15g/L MMC during operation, 20 patients(22 eyes)were given 0.25g/L MMC during operation, 19 patients(21 eyes)were given 0.4g/L MMC during operation. The patients were followed up for 6mo to 2a.
RESULTS: The recurrent rates of the three groups were 9%, 5%, 5% respectively. There was no statistically significant differences(P>0.05). The complication rates of the three groups were 5%, 36%, 33% respectively. There were statistically significant differences(P<0.05).
CONCLUSION: The treatment to the recurrent pterygium using low concentration MMC has the similar recurrence rates, but the complication rate was lower, it is an ideal operation method, and it is worth popularization and application.
[中图分类号]
[基金项目]
