[关键词]
[摘要]
角膜新生血管(corneal neovascularization)是影响角膜透明度的主要因素之一，也是同种异体角膜移植术后发生排斥反应的高危因素，因此角膜新生血管形成的调控已成为研究热点。microRNA是一组内源性非编码小分子RNA，在调控多种生物进程中起重要作用。近年来研究表明，microRNA与角膜新生血管形成有着紧密联系，本文将对目前的研究情况进行综述。
[Key word]
[Abstract]
Corneal neovascularization(CNV)is one of the most important causes that affecting corneal transparency, and it is a high risk factor of allogeneic corneal graft rejection. It has become a research focus for the regulation of CNV. microRNAs are a class of endogenous non-protein-coding micromolecule RNAs which play a critical role in regulating a series of life process. Researches in recent years show a close correlation between microRNA and CNV. In this article we reviewed the recent advances in these researches.
[中图分类号]
[基金项目]
重庆市医学科研计划项目(No.2013-1-033)
