方法：选取2013-05/2014-04在新乡医学院眼科医院住院的40例40眼视网膜静脉阻塞患者为研究对象，进行血脂、颈动脉彩色超声多普勒检查，包括总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)，颈总动脉内膜-中层厚度、颈动脉斑块、颈内动脉血流动力学参数。对照组30例30眼为我院同期健康体检者，同行以上检查。

结果：RVO组TC，TG，LDL-C明显高于对照组(P<0.05)，而HDL-C水平明显低于对照组(P<0.05)。RVO组颈动脉斑块形成发生率明显高于对照组。RVO组颈总动脉内膜-中层厚度(IMT)明显增加，颈内动脉收缩期峰值血流速度(PSV)及舒张末期血流速度(EDV)明显降低，阻力指数(RI)明显增高(P<0.05)。患眼同侧及对侧颈动脉各测量值比较无统计学差异(P>0.05)。对照组同侧及对侧颈动脉各测量值比较也无统计学差异(P>0.05)。两组性别、年龄无统计学差异(P>0.05)。

结论：脂质代谢紊乱、颈动脉改变与RVO的发病密切相关。

METHODS: Forty cases(40 eyes)with RVO who presented to Eye Hospital of Xinxiang Medical University between May 2013 and April 2014 were selected as the research objects. Proceeded blood lipids and color doppler ultrasonography examination, including total cholesterol(TC), triglycerides(TG), high-density lipoprotein cholesterol(HDL-C), low density lipoprotein cholesterol(LDL-C), common carotid artery intima-media thickness, carotid plaques, internal carotid artery blood flow mechanics parameters were detected. Thirty eyes(30 cases)were enrolled as control underwent above examinations.

RESULTS: TC, TG, LDL-C of RVO group was obviously higher than those of the control group(P<0.05), while HDL-C level was obviously lower than that of the control group(P<0.05). Incidence of carotid artery plaque formation in RVO group was obviously higher than that in the control group. Intima-media thickness(IMT)of common carotid artery was obviously increased in RVO group(P<0.05). Both peak systolic velocity(PSV)and end diastolic velocity(EDV)of internal carotid artery reduced(P<0.05), and Resistance index(RI)increased(P<0.05). The eyes of the sick side and the contralateral carotid artery measured value had no statistical difference(P>0.05). There were also no statistical difference between ipsilateral and contralateral carotid artery measured value of control group(P>0.05).There were no differences in age, sex between RVO group and control group(P>0.05).

CONCLUSION: Lipid metabolism disorder, carotid artery changes is closely related to the pathogenesis of RVO.