方法：选取翼状胬肉患者120例120眼，按照手术方式分为三组，每组各40例40 眼。比较各组间术前、术后Shirmer试验(Shirmer Ⅰ test，SⅠt)和泪膜破裂时间(tear break-up time， BUT)，角膜荧光素染色(corneal fluorescein staining ， CFS)及术后复发率，评估手术疗效和对泪膜功能的影响。

结果：术后1mo A组BUT 较术前无显著差异； B组和C组较术前的变化有显著差异( P<0.05)，但两组之间差异无统计学意义； 术后1mo，三组SⅠt和术前比较差异均无统计学意义； 术后1mo，A 组与B组及C组CFS存在显著性差异( P<0.05)； 但B组和C组差异无统计学意义。术后3mo，A组BUT较术前无显著差异； B组及C组较术前有显著性差异(P<0.05)，但B组及C组间差异无统计学意义； 术后3mo，A组S I t较术前无显著差异； B组及C组S I t较术前有显著性差异(P<0.05)，但两组间差异无统计学意义； 术后3mo，A组术前与B组及C组CFS无显著差异。随访10mo，经比较A组与B、C两组复发率存在显著差异( P<0.05)，B 组与C 组存在差异，但无统计学意义。夏季手术较冬季手术更容易复发。

结论：翼状胬肉切除联合角膜缘干细胞移植封闭Tenon囊是目前治疗翼状胬肉的较理想手术方式，降低复发率并使患者泪膜功能得到一定程度的改善。

METHODS: A total of 120 pterygium patients(120 eyes)were divided into three groups, each 40 cases(40 eyes). Data including Schirmer Ⅰ test(S Ⅰ t), tear break-up time(BUT), corneal fluorescein staining(CFS)were recorded preoperatively and postoperatively to evaluate the clinical efficacy of surgery and the effects of tear function changes.

RESULTS: There were no significant differences in BUT in group A before the operation and one month after operation. Groups B and C showed significant difference before and after operation, but differences were not statistically significant(all P<0.05); One month after operation, there was significant difference in CFS among group A, B and C(P<0.05), but the difference was not satistically significant between groups B and C; After 3mo, BUT in group A was not significant difference compared with the preoperative; but there was significant difference in groups B and C(P<0.05). When compared it between groups B and C, there showed no significant difference; Group A showed no significant difference in SⅠt compared with preoperative, SⅠt of groups B and C were significant differences compared with preoperative(P<0.05), but no significant difference between the two groups; After 3mo, CFS of preoperative group A and group B and group C had no significant difference. After 10mo follow-up, there was axsignificant difference(P<0.05)in recurrence rate in group A comparing with groups B and C, there were differences between groups B and C, but no statistically significant. Surgery is more likely to relapse in summer than in winter.

CONCLUSION: Pterygium excision combined with self-corneal limbal stem cell transplantation and Tenon capsule closed is an ideal surgical to reduce the recurrence and improve tear film function to some extent.