方法：回顾性分析2012-01/12于青岛大学附属医院眼科门诊就诊的224例256眼新生儿泪囊炎患者，分为1～3月龄组、4～6月龄组、7～9月龄组、10～12月龄组及>12月龄组共5组，首次治疗即行一次性泪道冲洗加探通术，比较不同月龄组患者治疗效果。

结果：患者256眼中，总治愈242眼(94.5%)，失败14眼(5.5%)，大于10月龄的患者鼻泪管阻塞明显增多，其治愈率明显降低； 随着年龄增长治疗次数增加(Spearman等级相关分析，r_s=0.746，P<0.01)； Hasner瓣阻塞226眼，全部治愈； 鼻泪管骨性部分阻塞30眼，治愈16眼(治愈率53.3%)； 两个部位阻塞的治愈率有明显差别； 无假道、感染病例。

结论：一次性泪道冲洗联合泪道探通术治疗新生儿泪囊炎安全、效果好，1～9月龄是最佳治疗年龄； 随着年龄增长，治愈率降低。

METHODS: In this retrospective case series study, 224 outpatients( 256 eyes )with neonatal dacryocystitis were selected from January 2012 to December 2012 in our hospital.The patients were divided into 5 groups(1～3mo, 4～60mo, 7～9mo, 10～12mo and >12mo). Initial lacrimal passage irrigation and probing were operated, the therapeutic effect of different groups were compared.

RESULTS: In this study, 256 eyes of 224 cases, 242 eyes(94.5%)were cured and 14 eyes(5.5%)were failed. Bony nasolacrimal duct obstruction happened more obviously in children aged more than 10mo with lower cure rate. More probing was required with the children aged(Spearman rank correlation analysis, γ_s=0.746, P<0.01). All of the 226 eyes with Hasner valve obstruction were cured. Bony nasolacrimal duct obstruction was 30 eyes, 16 eyes were cured(the cure rate was 53.3%). The cure rate of two parts of the obstruct had significant difference. There were no cases of infection and false passage.

CONCLUSION: The treatment of primary lacrimal passage irrigation and probing in neonatal daryocystitisis effective and safe, the optimal timing of treatment is 1～9mo. With the growth of age, the cure rate is decreased.