[关键词]
[摘要]
sirtuins家族(Ⅲ类组蛋白去乙酰化酶)作为表观遗传学的分支之一，近年来备受瞩目。SIRT1作为sirtuins家族中最知名的的成员已被验证参与了多种年龄相关性疾病。而SIRT1在年龄相关性白内障形成中所起到的作用也越来越受到关注。现就将SIRT1在年龄相关性白内障中的作用的研究进展进行简要概述。
[Key word]
[Abstract]
As one branch of epigenetics, the sirtuins family(Class Ⅲ histone deacetylase)receive much attention in recent years. SIRT1 as the most famous of the sirtuins family members has been verified involved in a variety of age-related diseases. While the SIRT1 formation is paid more and more attention in age-related cataract. Now, we briefly overviewed the research progress on the role of SIRT1 in age-related cataract.
[中图分类号]
[基金项目]
黑龙江省自然科学基金(No.D201254)
