方法：本课题为前瞻性研究。征集2013-10/2014-05就诊于我院的符合入选和排除标准的斜视患者共45例作为试验组，另外选择最佳矫正视力及眼位正常的成人45例作为对照组。采用中文版成人斜视生存质量量表进行问卷调查，比较斜视患者与正常成人以及斜视患者术前与术后6mo的生存质量差异。

结果：对照组正常成人的CAS-20社会心理评分及视功能评分都明显高于试验组斜视患者，差异均有统计学意义(P<0.01)。试验组斜视患者在术后6mo时较术前相比CAS-20社会心理评分及视功能评分都明显升高，差异均有统计学意义(P<0.01)。试验组斜视患者在术后6mo时社会心理评分及视功能评分仍显著低于对照组正常成人，差异均有统计学意义(P<0.01)。

结论：斜视在社会心理和视功能方面均影响了成人患者的生存质量，而斜视矫正手术有助于改善斜视患者的生存质量。

METHODS: In this prospective study, forty-five adults with a diagnosis of strabismus conform to the inclusion and exclusion standard were selected in our hospital from October 2013 to May 2014, as experimental group and 45 normal adults were enrolled as control group. A Chinese Adult Strabismus-20 questionnaire was used to evaluate the differences of quality of life between patients with strabismus and normal adults, and to evaluate the differences of quality of life in patients with strabismus preoperative and 6mo postoperative.

RESULTS: The scores of quality of life in adult patients with strabismus preoperative and 6mo postoperative were statistically significant lower than those of normal adults(P< 0.01). In 6mo postoperative, the scores of quality of life statistically significant increased than preoperative(P<0.01).

CONCLUSION: Strabismus can decrease the quality of life in psychosocial and visual functional for adults and the surgical treatment can improve quality of life in patients with strabismus.