[关键词]
[摘要]
骨髓间充质干细胞(bone marrow mesenchymal stem cells，BMSCs)富集于骨髓，可跨胚层分化，是一种具有多向分化潜能的成体干细胞。BMSC易于分离培养，可高效扩增和表达，具有组织修复能力。由于其具有免疫调节能力，能分泌神经营养因子，使BMSC可以作为移植治疗视网膜疾病的种子细胞。本文将对BMSCs的视网膜保护研究进展作一综述。
[Key word]
[Abstract]
Bone marrow mesenchymal stem cells(BMSCs)is a kind of adult stem cells mainly enriched in bone marrow, which possesses multiple differentiation potential and can differentiate into trans-germinal layer. It is easy for BMSC to be isolated and cultured, which has the ability of repairing various tissues with efficient proliferation and expression. BMSC could be used as seed cell for the transplantation therapy of retinal disease because of its properties of immunoregulation and neurotrophin secretion. This review focuses on research progress on retinal protection of BMSCs.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(No.81271026)
