方法：选择行白内障超声乳化联合人工晶状体植入前有干眼症的糖尿病患者54例60眼，随机分成A组、B组，A组28例30眼于术前使用羟糖苷滴眼液，B组26例30眼术前未使用羟糖苷滴眼液，两组术后均使用妥布霉素地塞米松、普拉洛芬及羟糖苷滴眼液，分别于术前3d，术后1，7，30，90d行干眼症状评分、泪膜破裂时间(break up time，BUT)、泪液分泌试验(Schirmer Ⅰ test，SⅠt)、角膜荧光素染色(fluorescein stain test，FL)评分。

结果：手术前3d两组干眼症状评分、BUT，SⅠt，FI评分检查结果相比，无显著性差异(P>0.05)，术后1，7d，A组干眼症状评分均小于B组，有显著性差异(P<0.05)。术后1，7，30d，A组与B组相比，BUT明显延长(P<0.05)，FL着色密集度明显减少(P<0.05)，SⅠt浸湿滤纸长度明显增加，差异均有统计学意义(P<0.05)。术后90d，两组干眼症状评分、BUT，SⅠt，FL评分值相比，差异均无统计学意义(P>0.05)。

结论：超声乳化联合人工晶状体植入术前应用人工泪液，对合并干眼的糖尿病患者术后的早期干眼症状能得到有效改善，并且泪膜功能得到有效恢复。

METHODS: Fifty-four diabetic patients with dry eye(60 eyes)were followed up before phacoemulsification. Preoperatively, group A(30 eyes in 28 cases)was treated with Hydroxyl Indican eye drops and group B(30 eyes in 26 cases)was not treated. Postoperatively, both group A and B were treated with Tobramycin Dexamethasone eye drops, Oprah Winfrey Ibuprofen eye drops and Hydroxyl Indican eye drops. Dry eye symptoms, break up time(BUT), Schirmer Ⅰ test(S Ⅰ t), fluorescein stain test(FI)were measured at 3d preoperatively, and 1, 7, 30, 90d postoperatively.

RESULTS: At 3d preoperatively, there was no statistical differences between the two groups for dry eye symptoms, BUT, SⅠt, FI(P>0.05). At 1 and 7d postoperatively, there were significant statistical differents between the two groups for dry eye symptoms(P<0.05). And dry eye symptoms scores of group A were less than that of group B. At 1, 7, 30d postoperatively, BUT was longer, FL was less, SIt was increased in group A, with significant statistical differences(all P<0.05). At 90d postoperatively, two groups of dry eye symptoms, BUT, SⅠt, FI had no statistical significance(P>0.05).

CONCLUSION: Using artificial tears before phacoemulsification can improve symptoms of the diabetic patients with dry eye and accelerate the recovery of the tear film.