方法：回顾性分析2010-01/2012-12在本院眼科中心验配RGP的110例185眼患者的临床资料，根据患者的屈光不正类型分为高度近视散光组49例92眼、圆锥角膜组36例64眼、特殊屈光不正组25例29眼，观察三组患者行RGP配戴后不同时间的视力、常规框架镜的矫正视力差异及不良反应情况。

结果：配戴RGP后即刻，高度近视散光组的矫正视力为4.94±0.16，圆锥角膜组4.98±0.15，特殊屈光不正组4.87±0.19，均显著优于配戴框架镜时的矫正视力(4.86±0.23，4.79±0.22，4.61±0.27)，且差异均具有统计学意义(P<0.05)。配戴RGP后第3，6mo三组患者的视力复查结果显示优于配戴框架镜时(P<0.05)。视散光组、圆锥角膜组、特殊屈光不正组配戴RGP后的视力分布明显优于配戴框架镜时(P<0.05)。

结论：RGP配戴矫正成人高度与特殊类型屈光不正较普通框架镜均具有显著的效果，不会增加干燥、异物感、易疲劳等不良反应的发生率，值得临床应用推广。

METHODS: Totally 110 cases(185 eyes)of Ophthalmology Center fitting of RGP from January 2010 to December 2012 were retrospective analyzed. According to the refractive error types, patients were divided into high myopia astigmatism group( 49 cases, 92 eyes), 36 cases(64 eyes)of keratoconus group, special ametropia group(25 cases, 29 eyes). Corrected visual acuity differences, adverse reactions of different temporal acuity and conventional frame in the three group were observed after wearing RGP.

RESULTS:After wearred RGP, corrected visual acuity of high myopic astigmatism group was 4.94±0.16, keratoconus group was 4.98±0.15, and special ametropia group was 4.87±0.19; they were significantly better than wearing frame mirror 4.86±0.23, 4.79±0.22, 4.61±0.27 and the differences were statistically significant(P<0.05). After 3 and 6mo of wearing RGP, patients eyesight after RGP was better than that of wearing frame glasses(P<0.05). As the astigmatism group, keratoconus group, special ametropia group wearing RGP, visual acuity after distribution were obviously better than the case when wearing frame glasses(P<0.05).

CONCLUSION: Wearring RGP can correct adult high and special type ametropia than ordinary frame glasses, which avoid the occurence of dry eye, foreign body sensation, and easy fatigue. It is worthy of clinical application.