方法：病例对照研究。选择2013-04 /2014-07在我院接受诊治的120例120眼慢性泪囊炎患者，随机分组，观察组(第五代泪道内窥镜下微钻联合全泪道置管术)62例62眼，对照组(传统泪囊鼻腔吻合术)58例58眼，观察比较两组的疗效及并发症。采用SPSS 13.0统计软件包进行统计学处理。

结果：观察组与对照组有效率分别为91.9%，96.6%，差异无统计学意义(P>0.05)。观察组与对照组术中出血发生率分别为35.5%，79.3%，差异有统计学意义(P<0.05)； 观察组与对照组术后眼睑水肿发生率分别为19.4%，55.2%，差异有统计学意义(P<0.05)。两组均未见术中术后严重并发症。

结论：第五代泪道内窥镜操作上较传统一体式泪道内窥镜更为灵活，直视病变情况下进行泪道微钻疏通鼻泪管，再联合全泪道置管术治疗慢性泪囊炎，不仅临床疗效好，而且较传统泪囊鼻腔吻合术更为安全，高效，是治疗慢性泪囊炎的可视化微创手术，值得临床推广应用。

METHODS:In this case-control study, 120 patients(120 eyes)with chronic dacryocystitis were collected from April 2013 to July 2014 in our department. The patients were randomly divided into observation group(the fifth generation endoscopic lacrimal microdrill with full intubation group, 62 cases 62 eyes)and control group(external dacryocystorhinostomy group, 58 cases 58 eyes). The effective rate and complication were observed and compared between two groups after operation. Statistical package SPSS 13.0 was used for statistical analysis.

RESULTS: The effective rate of observation group was 91.9%, and control group was 96.6%, there was no statistically significant difference between the two groups(P>0.05). Hemorrhage occurred in observation group and control group was 35.5% and 79.3%, respectively, additionally palpebral oedema was 19.4% and 55.2%, respectively, there were statistically significant differences between the two groups(P<0.05). There was no serious intraoperative and postoperative complications in two groups.

CONCLUSION: The fifth generation lacrimal endoscope is more flexible than traditional one-piece lacrimal endoscope during the operation, it can treat chronic dacryocystitis by directly observing nasolacrimal duct obstruction site and dredge the obstruction under microdrilling with full lacrimal intubation. It was not only good clinical curative effect, but also safer, more efficient than the external dacryocystorhinostomy, visualization and micro-invasive are its special advantage, and worthy for further clinical application.