目的：比较病理性高度近视黄斑裂孔性视网膜脱离(MHRD)手术中硅油与C₃F₈填充后视网膜复位率和高眼压发生率，为此类手术的填充物提供临床参考。

方法：采用回顾性病例对照设计。在不同时间段连续观察病理性高度近视MHRD患者，分别采用玻璃体切割联合眼内填充硅油和气体的两组患者分别进行观察，从手术后1wk； 1，3，6，12mo，视网膜复位率和眼压进行对比研究，观察患者视网膜复位及眼压的情况，得出最佳的填充方式。

结果：初次手术后，硅油组视网膜复位率高于气体组，但两组视网膜复位率差异无统计学意义； 患者眼压：硅油组高眼压发生率高于气体组，但差异无统计学意义。

结论：病理性高度近视MHRD患者玻璃体手术后使用哪种填充物，应采取个体化方案。

AIM:To analyze retinal reattachment rate and the incidence of high intraocular pressure vitreous surgery combined with silicone oil or C₃F₈ tamponade for patients with macular hole retinal detachment(MHRD)in pathologic high myopic eyes. And to provide clinical reference of such surgery in the choice of filler.

METHODS:A retrospective case-controlled study was designed. Continuous observation of the patients with high myopia MHRD at different periods was carried out. These patients who underwent vitrectomy with silicone oil or C₃F₈ intraocular tamponade were retrospectively analyzed in 1wk and 1, 3, 6, 12mo after surgery. The rate of retinal reattachment and the incidence of high intraocular pressure were analyzed between two groups, in order to obtain the best way to fill.

RSULTS:There was no statistically significant difference in the rate of retinal reattachment between silicone oil group and C₃F₈ tamponade group after initial surgery although silicone oil group was higher than C₃F₈ tamponade group in the rate of retinal reattachment. Silicone oil group was higher than C₃F₈ tamponade group of the incidence about high intraocular pressure after vitreous surgery. But there was no statistically significant difference in both groups.

CONCLUSION: We should take individual programs which filler were used after vitrectomy for patient with MHRD in high myopic eyes.