[关键词]
[摘要]
目的：运用光学相干断层扫描术(OCT)回顾性分析高度近视白内障超声乳化摘除联合人工晶状体植入术后BCVA<0.3组和BCVA≥0.3组黄斑中心凹视网膜厚度，分析其与术后视力的相关性。
方法：本研究为回顾性临床研究，共纳入行白内障超声乳化摘除联合人工晶状体植入的高度近视白内障患者70例70眼，于术后1wk； 1，3mo进行随访，记录最佳校正视力(BCVA)，并根据术后1wk BCVA分为BCVA<0.3组和BCVA≥0.3组，两组患者于术后1，3mo行OCT检查，测量黄斑中心凹视网膜厚度。采用相关分析研究术后BCVA恢复情况及其与黄斑中心凹视网膜厚度的相关性。
结果：患者术前，术后1wk； 1，3mo的BCVA<0. 05的眼的比分别为30%，14%，11%，7%。BCVA<0.3组术后1，3mo的黄斑中心凹视网膜厚度均较BCVA≥0.3组明显增加，两组术后3mo黄斑中心凹视网膜厚度均较术后1mo明显降低(P<0.01)。术后3mo BCVA和OCT检查黄斑中心凹视网膜厚度之间存在统计学上显著相关(r=-0.716，P<0.05)。
结论：在本研究中，术后所有患者在3mo的随访时间内视力得到一定程度的提高，且术后OCT检查黄斑中心凹视网膜厚度与术后视力的恢复情况相关。
[Key word]
[Abstract]
AIM:To retrospectively evaluate central foveal thickness in highly myopic eyes with best correct visual acuity(BCVA)
METHODS: In this retrospective clinical study, we consecutively recruited 70 low highly myopic cataract subjects(70 eyes)underwent Phaco. Postoperative visits were performed at 1wk, 1 and 3mo. Postoperative BCVA were recorded and further divided into 2 groups with BCVA< and ≥ than 0.3. Central foveal thickness was measured by OCT 1 and 3mo after surgery. Chi-square test was used to compare preoperative and postoperative BCVA. Pearsion's correlation was used to evaluate relationship between postoperative BCVA and central foveal thickness.RESULTS: The ratio of BCVA<0.05 was 30%,14%, 11% and 7% respectively for per-operation, 1wk, 1 and 3mo post-operation. After surgery, the central foveal thickness was significantly increased in group with BCVA<0.3 comparing to group with BCVA≥0.3. Three month post-operation, central foveal thickness was significantly decreased in both groups comparing to that in 1mo post-operation(P<0.01). There has significant correlation between 3mo postoperative BCVA and central foveal thickness(r=-0.716, P<0.05).
CONCLUSION: In this study, BCVA is improved after 3mo follow up. There has significant correlation between postoperative BCVA and central foveal thickness.
[中图分类号]
[基金项目]
国家自然科学基金(No.81371010); 上海市卫计委科研资助项目(No.20134466)
