方法：选取 2012级眼视光专业学生64人为研究对象，随机抽取32人为试验组，采用PBL 结合标准化患者进行眼科学基础教学，其余32人为对照组，采用传统教学方法。授课结束后应用自制调查问卷调查学生对教学效果的评价。统计两组学生的考试成绩及问卷调查结果。计数资料采取χ²检验，计量资料采用均数±标准差((-overx)±s)表示，行独立样本 t 检验，以 P<0.05 为差异有统计学意义。

结果：试验组理论考试成绩(83.22±3.75)和试验考试成绩(94.28±2.20)均明显高于对照组理论考试成绩(70.72±3.95)和试验考试成绩(85.44±3.52)， 差异有统计学意义(P均 <0.01)。试验组在实习考核中问诊及病史采集、眼科检查、临床诊断和病历书写的成绩均值均高于对照组，差异均有统计学意义(P均<0.01)。试验组学生对SP与PBL结合教学在调动学习积极性、加强团队协作意识、提高语言表达能力、综合分析能力、自学能力、创新能力、总结归纳能力、实践操作能力， 以及加强知识结构系统化方面的效果评价明显高于对照组， 差异有统计学意义(P均<0.05)。

结论：眼科学基础教学中将SP与PBL相结合，有助于学生更好地掌握专业知识，能调动学习积极性，提高自学能力、实践操作能力和临床思维能力。

METHODS: Sixty-four students of Optometry in grade 2012 were randomly divided into experimental group(n=32)and control group(n=32). Traditional teaching method was implemented in control group while PBL combined with SP was applied in experimental group. At the end of term students were interviewed using self-administered questionnaire to obtain their evaluation for teaching effect. Measurement data were expressed as (-overx)±s and analyzed by independent samples t test. Enumeration data were analyzed by χ² test, and P<0.05 significantly statistical differences.

RESULTS:The mean scores of theory test(83.22±3.75)and experimental test(94.28±2.20)in experimental group were significantly higher than theory test(70.72±3.95)and experimental test(85.44±3.52)in control group(all P<0.01). The mean scores of diagnose inquiry, ophthalmologic examination, clinical diagnosis and medical record writing were higher than that in the control group, difference had statistical significance(P<0.01). The students in experimental group had a significantly better self-assessment than the control group in learning enthusiasm, consciousness of team cooperation, ability of language expression, comprehensive analysis ability, self-learning ability, innovation ability, summarizing ability, practice ability, and systematic knowledge structure. The differences were statistically significant in questionnaire between the two groups(all P<0.05).

CONCLUSION:Using PBL combined with SP teaching mode in basic science of ophthalmology can highly improve learning enthusiasm of students and cultivate self-learning ability of students, practice ability and ability of clinical analysis.