方法：前瞻性对照研究，将年龄相关性白内障患者132例132眼，随机分为两组，试验组66例66眼采用Centurion超声乳化针头，对照组66例66眼采用Infinity超声乳化针头，两组均用Centurion超声乳化仪在同一手柄下，利用相同参数下完成常规的超声乳化联合人工晶状体植入术。记录两组术中的累积消耗能量(cumulative dissipated energy，CDE)，观察术后1wk，1mo的最佳矫正视力(best corrected visual acuity，BCVA)、角膜内皮密度(corneal endothelial cell density，CD)、中央角膜厚度(central corneal thickness，CCT)。采用独立样本t检验和χ²检验进行统计分析。

结果：两组患者的CDE差异有统计学意义(P<0.05)。术后1wk时BCVA(LogMAR)试验组优于对照组，差异有统计学意义(P<0.05)。术后1wk试验组CCT小于对照组，差异有统计学意义(P<0.01)，但术后1mo两组无统计学差异(P>0.05)。

结论：Centurion超声乳化针头能有效减少术中超声能量的释放，减少术后角膜内皮的损伤，对术后早期视力恢复更具有优势。

METHODS:A randomized prospective study was conducted. 132 patients(132 eyes)with age-related cataract, were randomly divided into study group(Centurion ultrasound tips)and control group(Infinity ultrasound tips), 66 cases(66 eyes)in each group. Under the same parameter of the Centurion phacoemulsification instrument, all the patients received normal microcoaxial phacoemulsification and intraocular lens implantation. The cumulative dissipated energy(CDE)was recorded during the operation. The best corrected visual acuity(BCVA), corneal endothelial cell density(CD)and central corneal thickness(CCT)were compared at 1wk and 1mo after surgery. Statistical analysis of the data was performed using Student's t test and Chi-square test.

RESULTS: There was significant difference on CDE(P<0.05)between these two groups. On 1wk after surgery, the study group showed better BCVA(LogMAR)as compared that of control group, the difference was statistically significant(P<0.05). The CCT of study group was smaller than the control group on 1wk after surgery(P<0.01), but there was no significant difference on 1mo(P>0.05).

CONCLUSION: Centurion ultrasound tips can significantly reduce the cumulative dissipated energy and cause less damage to corneal endothelial cells. These findings suggest that centurion vision system phacoemulsification surgery could get earlier visual rehabilitation postoperative.