方法：采用前瞻性研究方案，将51例63眼开角型青光眼合并白内障患者随机分为两组，对照组25例32眼采用超声乳化联合小梁切除术进行治疗，观察组26例31眼采用超声乳化联合Ex-PRESS引流进行治疗； 对比两组患者的临床疗效、视力改善水平及眼压控制结果，并完成为期3～6mo随访，观察并发症发生情况。

结果：处理因素和时间因素对患者的眼压均有影响(P<0.01)，且两者之间不存在交互作用(P>0.05)。治疗后3mo，两组患者的最佳矫正视力无统计学差异(P>0.05)，但观察组的临床疗效优于对照组，并发症发生率明显低于对照组，差异有统计学意义(P<0.05)。

结论：超声乳化联合Ex-PRESS引流器治疗开角型青光眼合并白内障疗效显著、安全可靠。

METHODS: The 51 patients(63 eyes)with primary open angle glaucoma with cataract were divided into 2 groups according to a prospective research programme. Twenty-five cases(32 eyes)were treated by phacoemulsification combined with trabeculectomy in the contol group, and 26 cases(31 eyes)were treated by phacoemulsification combined with Ex-PRESS implantation in the observation group. The clinical effect, level of vision improvement, and result of controlling intraocular pressure were compared, at the same time, the follow-up of 3～6mo was completed to observe the occurrence of complications.

RESULTS: The treatment method and detecting time were both showed the influence on the intraocular pressure of patients(P<0.01), and there was no interactional effect between two factors(P>0.05). At 3mo after treatment, there was no significant difference for best corrected visual acuity(BCVA)between groups(P>0.05), but the clinical efficacy of the observation group was better than that of the control group. The complication rate of the observation group was lower than that of the control group, and there was significant difference between two groups(P<0.05).

CONCLUSION: Phacoemulsification combined with Ex-PRESS implantation has high curative effect and security in the treatment of primary open angle glaucoma with cataract.