目的：研究埃及Tanta大学医院与隐形眼镜相关的感染性角膜炎患者的不同流行病学特点，评估这类疾病各方面的特点，以提高患者对这类疾病的认识，找出可行的解决方案。

方法：选取我院2009-01/2013-12期间在眼科门诊就诊的所有角膜炎患者仔细检查，并对所有与隐形眼镜相关的感染性角膜炎患者进一步检查和调查。

结果：本研究期间，总共108 496位有不同主诉的患者中，1463例(1.3%)患有不同形式的角膜炎，其中151例(0.1%)为隐形眼镜相关感染性角膜炎。结果发现患有隐形眼镜相关感染性角膜炎常见的年龄群<30岁，大多数是学生(64%)，家庭人数多且较为拥挤，农村居民高于城市居民，患者采用户外水源及污水处理不卫生。从病史分析发现：隐形眼镜相关感染性角膜炎通常为彻夜使用，储存或者配戴不卫生，或者隐形眼镜来源不安全，例如化妆品商店和理发店。结膜囊微生物培养结果提示阳性率92%，阴性率8%。大多数培养阳性的病例是由细菌和真菌混合感染引起，共53例(38.1%)，单纯细菌感染43例(30.9%)，真菌31例( 22.3%)，阿米巴12例(8.6%)。

结论：与隐形眼镜相关的感染性角膜炎常见于学生群体，与农村生活、户外供水、不卫生的污水处理等危险因素有关。彻夜配戴、储存或配戴不卫生及隐形眼镜来源不安全都可增加隐形眼镜相关感染性角膜炎的发病率。

AIM: To study the different epidemiological features of patients with contact lens-related microbial keratitis(CLRMK)in Tanta University Hospital in Egypt in order to assess different aspects of that problem, improve patients' awareness and in a trial to find practical solutions.

METHODS: All cases with keratitis attending the Outpatient Clinic of Ophthalmology Department at Tanta University Hospital during a period of 5y starting from the first of January 2009 to the end of December 2013 were selected and carefully examined and cases with CLRMK were further examined and investigated.

RESULTS: Out of total 108 496 attendants during this period with different complaints, there were 1463(1.3%)cases suffering from different forms of keratitis and 151(0.1%)with CLRMK. Results revealed that CLRMK is common in age group <30y, more in students(49%), families with large number and large crowding index, rural than urban residence, patients with outdoor water sources and insanitary sewage disposal. From history taking, it was found that CLRMK was more common with overnight use, insanitary storage cases or solutions and unsafe sources like shops of cosmetics and hair dressers. Cultural results were positive in 92% and negative in 8% of cases. The positive culture results were mixed infection(bacterial and fungal)in most of cases(53, 35.1%), bacterial only(43, 28.5%), fungal only(31, 20.5%)and acathamebic in 12(8%)of cases.

CONCLUSION: CLRMK is more frequent in students, rural areas, in outdoor water supply, insanitary sewage disposal. Overnight use, insanitary storage cases or solutions and unsafe sources were associated with increased incidence of CLRMK.