[关键词]
[摘要]
目的：探讨鼻内镜下泪囊鼻腔吻合术中应用丝裂霉素C治疗慢性泪囊炎置管术后复发患者的临床效果。
方法：慢性泪囊炎置管术后复发患者62例62眼随机分为两组，在施行鼻内窥镜下泪囊鼻腔吻合术中联合应用丝裂霉素C置于吻合口骨窗处(治疗组)31例； 单纯行鼻内窥镜下泪囊鼻腔吻合术(对照组)31例。随访3～12mo。
结果：术后6mo时治疗组的治愈率及有效率分别为90%、97%，对照组的治愈率及有效率分别为74%、94%。治疗组的治愈率高于对照组(Z=14.66，P<0.05)。
结论：鼻内窥镜下泪囊鼻腔吻合术中联合应用丝裂霉素C有利于预防吻合口瘢痕粘连及提高远期疗效，是一种有效辅助治疗方法。
[Key word]
[Abstract]
AIM:To observe clinical effects of endoscopic dacryocystorhinostomy combined with adjunctive mitomycin C(MMC)on the treatment of recurrent chronic dacryocystitis after lacrimal duct intubation.
METHODS:Sixty-two eyes of 62 cases with recurrent chronic dacryocystitis after lacrimal duct intubation were randomly divided into two groups: treatment group(31 cases)and control group(31 cases). Patients in the treatment group were undergone endoscopic dacrystorhinostomy combined with MMC placed on the anastomotic bone hole.Patients in the control group only received endoscopic dacryocystorhinostomy. The follow-up period arranged from 3 to 12mo.
RESULTS: At 6mo postoperative, the cure rate and effective rate of the treatment group was 90% and 97% respectively, and those of the control group were 74% and 94% respectively. The effective rate of the treatment group was higher than that of the control group significantly(Z=14.66,P<0.05).
CONCLUSION: Endoscopic dacryocystorhinostomy combined with MMC is an effective supplemental method which can prevent postoperative anastomotic cicatricial adhesion and improve the long-term outcome.
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