Hemodialysis is an important therapeutic method of acute and chronic renal failure and other serious diseases.Many studies have shown that hemodialysis may cause changes of intraocular pressure and intracranial pressure. It may provide new approach for the establishment of glaucoma model by studying intraocular pressure and intracranial pressure changes during hemodialysis, which may contribute to the research on glaucomatous optic nerve damage. In this article, we reviewed the change of intraocular pressure and intracranial pressure during hemodialysis.