方法：将66例年龄相关性白内障患者，按照随机对照原则分为观察组与对照组，分别采用小切口劈核与超声乳化联合人工晶状体植入术治疗，对比两组患者术后视力、散光情况，手术前后角膜内皮变化，术中术后并发症及术后2wk的生活质量。

结果：两组术后1d，1wk，1mo的术眼裸眼视力，术后1mo的散光度，术后2wk的生活质量比较，差异均无统计学意义(P>0.05)； 术后2wk，两组患者术后角膜内皮细胞数、细胞密度及六角形细胞比例均较术前明显下降(均P<0.05)； 但观察组术后2wk的角膜内皮指标均高于对照组(均P<0.05)。

结论：小切口劈核术与超声乳化术对年龄相关性白内障都具有视力恢复好、术后散光小、患者生活质量高等优势，但超声乳化术对角膜内皮损伤较大，术后角膜内皮厚度更小。

METHODS: Sixty-six cases of age-related cataract patients were divided into observation group and control group according to a randomized and controlled principle. Patients of the two groups were treated with small incision nucleus chopping surgery and phacoemulsification surgery individually. Visual acuity, astigmatism after surgery, corneal endothelium changes before and after surgery, intraoperative and postoperative complications and quality of life 2wk after surgery of the two groups were compared.

RESULTS: The uncorrected visual acuity at 1d, 1wk and 1mo after surgery, astigmatism at 1mo after surgery, quality of life at 2wk after surgery of the two groups showed no statistical significances(P>0.05). Two weeks after surgery, the number of corneal endothelial cells, corneal endothelial cells density and the ratio of hexagonal cells of two groups decreased significantly compared with pre-surgery(P<0.05), but the corneal endothelial indicators of observation group was higher than those of the control group(P<0.05).

CONCLUSION: Small incision nucleus chopping technique and phacoemulsification for age-related cataracts have good visual acuity, small postoperative astigmatism, higher quality of life for patients, but the former has less damage on corneal endothelial, which has thicker corneal endothelium after surgery.